ArticlePloS one2017
Evaluation of a real-time method of simultaneous amplification and testing in diagnosis of Mycoplasma pneumoniae infection in children with pneumonia.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Association of doxycycline treatment with time to first documented MP-RNA negative conversion in pediatric Mycoplasma pneumoniae pneumonia: a retrospective cohort study.Italian journal of pediatrics · 2026Article
- Comparison between DNA- and RNA-based nucleic acid amplification tests for detecting Mycoplasma pneumoniae in pediatric specimens.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Research Progress on Point-of-Care Testing Technology for Mycoplasma Pneumonia.International journal of general medicine · 2026Review
- Epidemiological association of the COVID-19 pandemic onBMJ open · 2025Article
- To evaluate the performance of simultaneous amplification and testing assay for group B Streptococcus detection: comparison with real-time PCR and ddPCR assays.Annals of clinical microbiology and antimicrobials · 2024Article
- Application value of antibody titres and RNA detection in the early prediction of Mycoplasma pneumoniae pneumonia in children: a retrospective study.BMC infectious diseases · 2023Article
- Analysis of Ureaplasma urealyticum, Chlamydia trachomatis, Mycoplasma genitalium and Neisseria gonorrhoeae infections among obstetrics and gynecological outpatients in southwest China: a retrospective study.BMC infectious diseases · 2022Article
- Comparison of different detection methods for Mycoplasma pneumoniae infection in children with community-acquired pneumonia.BMC pediatrics · 2021Article
- The Level of D-Dimer Is Positively Correlated With the Severity ofFrontiers in cellular and infection microbiology · 2021Article
- Article
- Comparison of enzyme-linked immunosorbent assay with indirect immunofluorescence assay for the diagnosis of Mycoplasma pneumoniae infection.Journal of clinical laboratory analysis · 2019Article
- Early Diagnosis ofFrontiers in pediatrics · 2019Article
- Detection ofInfection and drug resistance · 2019Article
- Comparison of rRNA-based and DNA-based nucleic acid amplifications for detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Ureaplasma urealyticum in urogenital swabs.BMC infectious diseases · 2018Article
- [Value of simultaneous amplification and testing in early diagnosis of Mycoplasma pneumoniae pneumonia and related influencing factors].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Article
- Serological diagnosis of Mycoplasma pneumoniae infection by using the mimic epitopes.World journal of microbiology & biotechnology · 2018Article
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Mycoplasma pneumoniae (M. pneumoniae) infection can cause community acquired pneumonia in children. A real-time method of simultaneous amplification and testing of M. pneumoniae (SAT-MP) was developed to diagnose M. pneumoniae targeting a region of the ribosomal RNA. The SAT-MP assay can accurately identify M. pneumoniae with a detection range from 101 to 107 CFU/ml. In this study, the specimens from 315 children with pneumonia were collected and analyzed by SAT-MP in parallel with real-time PCR method and IgM ELISA assay. The positive rates of these specimens examined by SAT-MP assay, real-time PCR method and IgM ELISA assay were 16.51%, 15.56% and 12.70% respectively. While there was statistical significance (p = 0.04) between SAT-MP assay and IgM ELISA assay, no statistical significance (p = 0.25) was found between SAT-MP assay and real-time PCR method and these two methods had high consistency (kappa value = 0.97). These findings indicate that the newly developed SAT-MP assay is a rapid, sensitive and specific method for identifying M. pneumoniae with potential clinical application in the early diagnosis of M. pneumoniae infection.
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