ArticlePloS one2017
First evidence of the Hepatitis E virus in environmental waters in Colombia.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Hepatitis E Virus in Water Environments: A Systematic Review and Meta-analysis.Food and environmental virology · 2022Pooled it
- A One Health Approach to Hepatitis E Virus in Venezuela: Low Seroprevalence in Humans and First Genomic Evidence of Hepatitis E Virus Genotype 3 in a Domestic Swine.Microorganisms · 2026Article
- Real-Time PCR-Based Detection of Hepatitis E Virus in Groundwater: Primer Performance and Method Validation.International journal of molecular sciences · 2025Article
- Trends and Challenges in the Detection and Environmental Surveillance of the Hepatitis E Virus.Microorganisms · 2025Review
- Article
- A Survey of Hepatitis B Virus and Hepatitis E Virus at the Human-Wildlife Interface in the Peruvian Amazon.Microorganisms · 2024Article
- Water-Based Epidemiological Investigation of Hepatitis E Virus in South Africa.Food and environmental virology · 2024Article
- Bioinformatics-based screening tool identifies a wide variety of human and zoonotic viruses in Trujillo-Peru wastewater.One health (Amsterdam, Netherlands) · 2024Article
- Epidemiology Update of Hepatitis E Virus (HEV) in Uruguay: Subtyping, Environmental Surveillance and Zoonotic Transmission.Viruses · 2023Review
- Seroprevalence of Hepatitis E virus in children and adolescents living in urban Bogotá: An explorative cross-sectional study.Frontiers in public health · 2023Article
- Hepatitis E virus in pigs and the environment: An updated review of public health concerns.Narra J · 2022Review
- Hepatitis E Virus: An emerging enigmatic and underestimated pathogen.Saudi journal of biological sciences · 2022Review
- Occurrence of various viruses and recent evidence of SARS-CoV-2 in wastewater systems.Journal of hazardous materials · 2021Review
- The Foodborne Transmission of Hepatitis E Virus to Humans.Food and environmental virology · 2021Review
- Viruses in wastewater: occurrence, abundance and detection methods.The Science of the total environment · 2020Review
- Assessment of the Presence of Hepatitis E virus in Surface Water and Drinking Water in Portugal.Microorganisms · 2020Article
- Identifying spatial heterogeneity of groundwater and its response to anthropogenic activities.Environmental science and pollution research international · 2019Article
- Article
- Challenges in research and management of hepatitis E virus infection in Cuba, Mexico, and Uruguay.Revista panamericana de salud publica = Pan American journal of public health · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatitis E virus (HEV) is one of the main causes of acute viral hepatitis of enteric transmission. HEV has been detected in environmental samples in several countries from Europe and Asia, constituting a risk factor for waterborne infection. In Colombia, HEV has been identified in samples obtained from patients as well as from swine, but no environmental studies have been carried out. To determine if HEV is present in environmental waters, samples from the main source of drinking water plant and of wastewater system of eight municipalities and two villages of Antioquia state (North West Colombia), were collected between December 2012 and April 2014. The HEV genome was detected by RT-PCR in 23.3% (7/30) of the samples from the main source of drinking water plants and in 16.7% (5/30) from sewage. Viral concentrates obtained from three positive sewage samples were used to inoculate HepG2 cell cultures that were followed for one month; however, the viral genome was not detected in any cell culture. This study demonstrates the circulation of HEV in both source of drinking water plants and wastewater in Antioquia state, Colombia. The presence of HEV in environmental waters could be a risk for waterborne transmission in this population. The findings of the present study, together with the evidence of HEV circulation in human and swine in Colombia, should be consider by public health authorities for the development of surveillance programs and the inclusion of HEV infection diagnosis in the guidelines of viral hepatitis in the country. This is the first report of HEV in environmental samples in Colombia and the second one in Latin America.
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Registered trials
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