Evidence map›Paper›PMID 28520719›Full record

Observational studyPloS one2017

Sex differences in management and outcomes of patients with atrial fibrillation in the Middle East: Gulf survey of atrial fibrillation events (Gulf SAFE).

Abdulla Shehab, Mohammad Zubaid, Akshaya Srikanth Bhagavathula, Wafa A Rashed, Alawi A Alsheikh-Ali, Wal AlMahmeed, Kadhim Sulaiman, Ibrahim Al-Zakwani, Ahmed AlQudaimi, Nidal Asaad and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Atrial fibrillation and flutter in the Eastern Mediterranean: burden, disparities, and risk factor contributions from 1990 to 2021.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
  2. Article
  3. Sex Differences in Atrial Fibrillation.Current cardiology reports · 2023
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 6 countries.

Abdulla ShehabDepartment of Internal Medicine, Faculty of Medicine, UAE University, Al Ain, United Arab Emirates.
Mohammad ZubaidDepartment of Medicine, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.
Akshaya Srikanth BhagavathulaDepartment of Clinical Pharmacy, University of Gondar-College of Medicine and Health Sciences, Gondar, Ethiopia.
Wafa A RashedDepartment of Medicine, Mubarak Al-Kabeer Hospital, Ministry of Health, Kuwait University, Kuwait City, Kuwait.
Alawi A Alsheikh-AliDivision of Cardiology, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
Wal AlMahmeedDivision of Cardiology, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
Kadhim SulaimanRoyal Hospital, Muscat, Oman.
Ibrahim Al-ZakwaniDepartment of Pharmacology and Clinical Pharmacy, College of Medicine and Health Sciences, Sultan Qaboos University and Gulf Health Research, Muscat, Oman.
Ahmed AlQudaimiAl Thawra Hospital, Sana'a, Yemen.
Nidal AsaadDepartment of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, Doha, Qatar.
Haitham AminMohammed Bin Khalifa Cardiac Center, Manama, Bahrain.
Gulf Survey of Atrial Fibrillation Events (Gulf SAFE) investigators
Shaikh Khalifa Medical City · AEAl-Razi University · YEHamad Medical Corporation · QAKuwait University · KWMubarak Al Kabeer Hospital · KWRoyal Hospital · OMSultan Qaboos University · OMUnited Arab Emirates University · AEUniversity of Gondar · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Differences in the management of atrial fibrillation (AF) between men and women were investigated by using Gulf SAFE data in the Middle East. The study included 2,043 patients presenting with AF to emergency room (ER) were prospectively enrolled and followed for one-year. Women were older, have higher body mass index (BMI), comorbidities, and health complications than men. With regard to management of AF, cardioversion was recommended more often for men (16.7% vs. 9.3%), and underwent electrical cardioversion (2.2% vs. 1.1%). Women were prescribed digoxin more frequently than men (25.6% vs. 17.4%) and a significant number women received warfarin alone (31.1% vs. 8.7%). No difference between the sexes was noticed in One-year rates of stroke/transient ischemic attacks (TIA) and all-cause of mortality after one-year follow-up (3.1% men vs. 3.3% women, and 7.5% vs. 7.4%). Older age (≥ 65 years), smoking, alcohol use, CHADS2 scores ≥5 were some of the significant risk factors in men with AF. Suboptimal use of anticoagulants, higher mortality and stroke/TIA events at one year are high but similar between the sexes. ER management revealed high use of rate control strategy and high rate of hospital admission was noticed in women.

Indexed as

AdultAgedAge FactorsAlcohol DrinkingAtrial FibrillationBody Mass IndexDigoxinFemaleHumansMaleMiddle AgedMiddle EastSex FactorsSmokingWarfarinDigoxinWarfarin

Identifiers

PMID28520719
PMCPMC5435140
OpenAlexW2616668165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.