Observational studyThe Journal of head trauma rehabilitation
Family History of Migraine Associated With Posttraumatic Migraine Symptoms Following Sport-Related Concussion.
Observational study in The Journal of head trauma rehabilitation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05646160 (Effects of Myofascial Trigger Points Therapy in Migraine.), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Myofascial Trigger Points Therapy in Migraine.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Acute and chronic management of posttraumatic headache in children: A systematic review.Headache · 2021Pooled it
- Subtypes of Sport-Related Concussion: a Systematic Review and Meta-cluster Analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Concussion Guidelines Step 2: Evidence for Subtype Classification.Neurosurgery · 2020Guideline
- Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study.Neurology. Genetics · 2026Article
- Sex differences in fixational eye movements following concussion.Journal of vision · 2025Article
- Normative Data for a Multi-Domain Concussion Assessment in the Female Community Sport of Ladies Gaelic Football.Sports (Basel, Switzerland) · 2025Article
- Biomarkers and Endophenotypes of Post-traumatic Headaches.Current pain and headache reports · 2024Review
- American Headache Society white paper on treatment of post-traumatic headache from concussion in youth.Headache · 2024Article
- Traumatic brain injury: molecular biomarkers, genetics, secondary consequences, and medical management.Frontiers in neuroscience · 2024Review
- Does Physiologic Post-Concussion Disorder Cause Persistent Post-Traumatic Headache?Current pain and headache reports · 2023Review
- Neurovascular Compression-Induced Intracranial Allodynia May Be the True Nature of Migraine Headache: an Interpretative Review.Current pain and headache reports · 2023Review
- Determination of the Frequency of Migraine Attacks in Pregnant Women and the Ways They Cope with Headaches: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2023Article
- Reframing postconcussional syndrome as an interface disorder of neurology, psychiatry and psychology.Brain : a journal of neurology · 2022Article
- False-Positive Rates and Associated Risk Factors on the Vestibular-Ocular Motor Screening and Modified Balance Error Scoring System in US Military Personnel.Journal of athletic training · 2022Article
- Erenumab for headaches in idiopathic intracranial hypertension: A prospective open-label evaluation.Headache · 2021Article
- Persistent post-traumatic headache: a migrainous loop or not? The clinical evidence.The journal of headache and pain · 2020Review
- Linking Traumatic Brain Injury, Sleep Disruption and Post-Traumatic Headache: a Potential Role for Glymphatic Pathway Dysfunction.Current pain and headache reports · 2019Review
- Prognostic Factors in Pediatric Sport-Related Concussion.Current neurology and neuroscience reports · 2018Review
- Factors Associated with Sport-Related Post-concussion Headache and Opportunities for Treatment.Current pain and headache reports · 2018Review
- Exploring Vestibular Ocular Motor Screening in Adults With Persistent Complaints After Mild Traumatic Brain Injury.The Journal of head trauma rehabilitationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectiveTo determine whether family history of migraine increased the likelihood of posttraumatic migraine (PTM) symptom presentation in adolescents following concussion, and examine the influence of family history of migraine and PTM on postinjury outcomes.
settingOutpatient concussion clinic.
participantsA total of 153 patients with concussion (103 males and 50 females) aged 15.72 ± 1.48 years (range 12-18 years).
designCross-sectional, observational study of patients presenting for initial evaluation 4.72 ± 3.05 days (range 1-14) postinjury. MAIN MEASURES: Computerized neurocognitive testing, symptom report, and vestibular/oculomotor screening.
resultsPatients with a family history of migraine were 2.6 times (odds ratio = 2.60, confidence interval = 1.35-5.02, P = .003) more likely to present with PTM compared with patients without a family history. Results of multivariate analyses of covariance, controlling for concussion history, revealed significant main effects for PTM on (1) Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT)/Post-Concussion Symptom Scale (PCSS) (F = 15.43, P <.001) and (2) Vestibular/Ocular Motor Screening (VOMS) (F = 8.52, P < .001). There was no main effect for family history of migraine on ImPACT/PCSS (P = .22) and VOMS (P = .83) or interaction between family history of migraine and PTM on ImPACT/PCSS (P = .84) and VOMS (P = .52).
conclusionFamily history of migraine is associated with PTM symptoms following sport-related concussion, suggesting a genetic predisposition for migraine may serve as a catalyst or trigger for onset of PTM. However, only presence of PTM, rather than family history of migraine, was related to worse neurocognitive and vestibular/oculomotor outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.