Evidence map›Paper›PMID 28518130›Full record

ArticleClinical and translational gastroenterology2017

How to Conduct and Interpret Systematic Reviews and Meta-Analyses.

Siddharth Singh

Abstract read
In one paragraph

Article in Clinical and translational gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Review
  12. Review
  13. Kinetic Modeling ofMetabolites · 2022
    Review
  14. Article
  15. How to Write a Systematic Review: A Narrative Review.International journal of preventive medicine · 2021
    Review
  16. Positioning Therapies in the Management of Crohn's Disease.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2020
    Review
  17. Article
  18. Article
  19. How clean is clean: a review of the social science of environmental cleanups.Environmental research letters : ERL [Web site] · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Siddharth SinghDivision of Gastroenterology, University of California San Diego, La Jolla, California, USA.

Funding

San Diego Biomedical Informatics Education & Research (SABER)T15LM011271 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHAMIM NEMATI · 2012 to 2026
$9.7M
NLM NIH HHS T15 LM011271
6 · The paper itself

Abstract

Systematic reviews with or without meta-analyses serve a key purpose in critically and objectively synthesizing all available evidence regarding a focused clinical question and can inform clinical practice and clinical guidelines. Performing a rigorous systematic review is multi-step process, which includes (a) identifying a well-defined focused clinically relevant question, (b) developing a detailed review protocol with strict inclusion and exclusion criteria, (c) systematic literature search of multiple databases and unpublished data, in consultation with a medical librarian, (d) meticulous study identification and (e) systematic data abstraction, by at least two sets of investigators independently, (f) risk of bias assessment, and (g) thoughtful quantitative synthesis through meta-analysis where relevant. Besides informing guidelines, credible systematic reviews and quality of evidence assessment can help identify key knowledge gaps for future studies.

Identifiers

PMID28518130
PMCPMC5454386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.