Evidence map›Paper›PMID 28517988›Full record

ArticleThe New bioethics : a multidisciplinary journal of biotechnology and the body2017

The Promise and the Hype of 'Personalised Medicine'.

Tim Maughan

Abstract read
In one paragraph

Article in The New bioethics : a multidisciplinary journal of biotechnology and the body, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. What Is Precision Psychotherapy?The Journal of medicine and philosophy · 2026
    Article
  3. Sorting out and navigating uncertainty in precision medicine.History and philosophy of the life sciences · 2026
    Article
  4. Article
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  7. Review
  8. Article
  9. Earth Dreams: Reimagining ARPA for Health of People, Places and Planet.International journal of environmental research and public health · 2021
    Article
  10. Prioritisation and design of clinical trials.European journal of epidemiology · 2021
    Article
  11. Hope versus reality: Parent expectations of genomic testing.Patient education and counseling · 2021
    Article
  12. Information, communication, and cancer patients' trust in the physician: what challenges do we have to face in an era of precision cancer medicine?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Tim Maughana CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford , Oxford , UK.

Funding

Department of Health 11/100/50Medical Research Council G0701770Medical Research Council MR/M016587/1
6 · The paper itself

Abstract

Personalised medicine is widely considered as the way of the future for medicine. However, progress in cancer, with a few outstanding exceptions, has fallen below expectations because of the challenges of tumour heterogeneity and clonal evolution. In both benign and malignant disease, diseases caused by single genetic alterations are more amenable to precision medicine approaches. However, most common diseases are caused by a complex interplay of multiple genetic and environmental factors making personalised medicine far more challenging. The current optimism for personalised medicine is distorting clinical consultations, resource allocation and research funding prioritisation. A research active clinician must act both as an agent of change and development, and as a communicator of realism. Thus personalised medicine that includes a sober appreciation of what genomics can achieve, together with continued focus on the individual as a person not just as a genome, will contribute to further improvements in health and healthcare.

Indexed as

Precision MedicineResource AllocationDelivery of Health CareGenomicsHumansNeoplasmscancerhypepersonalised medicineprecision medicinepromisestratified medicine

Identifiers

PMID28517988
PMCPMC5448398

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.