ArticleMolecular and cellular biology1988
Expression of the c-myb and c-myc genes is regulated independently in differentiating mouse erythroleukemia cells by common processes of premature transcription arrest and increased mRNA turnover.
Article in Molecular and cellular biology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The trial behind it
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Who cites it
19 citing papers in PubMed, 68 citations in OpenAlex.
- The mechanism of MYB transcriptional regulation by MLL-AF9 oncoprotein.Scientific reports · 2019Article
- Distal regulation of c-myb expression during IL-6-induced differentiation in murine myeloid progenitor M1 cells.Cell death & disease · 2016Article
- A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition.Genes & development · 2016Article
- MYB elongation is regulated by the nucleic acid binding of NFκB p50 to the intronic stem-loop region.PloS one · 2015Article
- A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity.Nucleic acids research · 2008Article
- Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activation.The Biochemical journal · 2001Article
- Constitutive c-Myb amino-terminal phosphorylation and DNA binding activity uncoupled during entry and passage through the cell cycle.Oncogene · 2001Article
- Article
- Control of transcription arrest in intron 1 of the murine adenosine deaminase gene.Molecular and cellular biology · 1994Article
- Functional analysis of a stable transcription arrest site in the first intron of the murine adenosine deaminase gene.Molecular and cellular biology · 1993Article
- Regulation and expression of a growth arrest-specific gene (gas5) during growth, differentiation, and development.Molecular and cellular biology · 1992Article
- Distinct modes of transcription read through or terminate at the c-myc attenuator.The EMBO journal · 1992Article
- Sequence requirements for transcriptional arrest in exon 1 of the human adenosine deaminase gene.Molecular and cellular biology · 1991Article
- c-fos gene transcription in murine macrophages is modulated by a calcium-dependent block to elongation in intron 1.Molecular and cellular biology · 1991Article
- Enhanced translation and increased turnover of c-myc proteins occur during differentiation of murine erythroleukemia cells.Molecular and cellular biology · 1990Article
- A cis-acting element in the promoter region of the murine c-myc gene is necessary for transcriptional block.Molecular and cellular biology · 1989Article
- Differential binding of nuclear factors to the intron 1 sequences containing the transcriptional pause site correlates with c-myb expression.Proceedings of the National Academy of Sciences of the United States of America · 1989Article
- Hematopoietic lineage-specific heterogeneity in the 5'-terminal region of the chicken proto-myb transcript.Molecular and cellular biology · 1989Article
- Continued withdrawal from the cell cycle and regulation of cellular genes in mouse erythroleukemia cells blocked in differentiation by the c-myc oncogene.Molecular and cellular biology · 1989Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanisms that modulate c-myb mRNA levels in mouse erythroleukemia cells induced toward erythroid differentiation were compared with those that act on c-myc. Both genes exhibited regulation at the levels of premature transcription arrest and RNA turnover. However, these common processes allowed temporally distinct control of gene expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.