Evidence map›Paper›PMID 28516426›Full record

ArticleJournal of autism and developmental disorders2018

Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder.

Logan K Wink, Ernest V Pedapati, Ryan Adams, Craig A Erickson, Kahsi A Pedersen, Eric M Morrow, Desmond Kaplan, Matthew Siegel, Autism and Developmental Disorders Inpatient Research Collaborative (ADDIRC)

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
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  7. Review
  8. Emotion Dysregulation is Substantially Elevated in Autism Compared to the General Population: Impact on Psychiatric Services.Autism research : official journal of the International Society for Autism Research · 2021
    Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Logan K WinkCincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave MLC 4002, Cincinnati, OH, 45229, USA. logan.wink@cchmc.org.
Ernest V PedapatiCincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave MLC 4002, Cincinnati, OH, 45229, USA.
Ryan AdamsCincinnati Children's Hospital Medical Center, 3333 Burnet Ave MLC 4002, Cincinnati, OH, 45229, USA.
Craig A EricksonCincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave MLC 4002, Cincinnati, OH, 45229, USA.
Kahsi A PedersenMaine Medical Center Research Institute, Tufts University School of Medicine, 509 Forest Avenue, Portland, ME, 04101, USA.
Eric M MorrowEmma Pendleton Bradley Hospital, Rhode Island Consortium for Autism Research and Treatment (RI-CART), and the Hassenfeld Child Health Innovation Institute, Alpert Medical School of Brown University, 1011 Veterans Memorial Pkwy., East Providence, RI, 02915, USA.
Desmond KaplanSheppard Pratt Health System, University of Maryland School of Medicine, 6501 N. Charles Street, Baltimore, MD, 21204, USA.
Matthew SiegelMaine Medical Center Research Institute, Spring Harbor Hospital, Tufts University School of Medicine, 123 Andover Road, Westbrook, ME, 04092, USA.
Autism and Developmental Disorders Inpatient Research Collaborative (ADDIRC)
Cincinnati Children's Hospital Medical Center · USUniversity of Cincinnati · USBradley Hospital · USMaine Medical Center · USMaine Medical Center Research Institute · USUniversity of Maryland, Baltimore · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI MEINZEN-DERR, JAREEN, STRAWN, JEFFREY ROBERT · 2015 to 2024
$37.5M
Simons Foundation (US) 296318
6 · The paper itself

Abstract

Nearly 11% of youth with Autism Spectrum Disorder (ASD) undergo psychiatric hospitalization, and 65% are treated with psychotropic medication. Here we characterize psychotropic medication usage in subjects enrolled in the Autism Inpatient Collection. Participant psychotropic medication usage rates topped 90% at admission and discharge, though there was a decline at 2-month follow-up. Antipsychotics, ADHD medications, and sleep aids were the most commonly reported classes of medications. The impact of age, gender, and non-verbal IQ on medication usage rates was minimal, though age and IQ may play a role in prescribing practices. Future work is indicated to explore medication usage trends, the impact of clinical factors on medication use rates, and the safety of psychotropic medications in youth with ASD.

Indexed as

AdolescentAutism Spectrum DisorderChildChild, PreschoolDrug UtilizationFemaleHospitals, PediatricHospitals, PsychiatricHumansInpatientsMalePsychotropic DrugsYoung AdultPsychotropic DrugsAntipsychoticsAutismAutism Spectrum DisorderMedicationPsychiatric hospitalization

Identifiers

PMID28516426
OpenAlexW2616529898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.