Evidence map›Paper›PMID 28516332›Full record

ArticleJournal of neurology2017

Prevalence and mortality of patients with multiple sclerosis in France in 2012: a study based on French health insurance data.

Stéphanie Foulon, Géric Maura, Marie Dalichampt, François Alla, Marc Debouverie, Thibault Moreau, Alain Weill

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The epidemiology, pathology and pathogenesis of MS: Therapeutic implications.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Altered Immune Phenotypes andFrontiers in immunology · 2021
    Article
  15. Article
  16. Review
  17. Article
  18. Neurofibromatosis I and multiple sclerosis.Orphanet journal of rare diseases · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Stéphanie FoulonDepartment of Studies in Public Health, French National Health Insurance, Paris, 75986, Cedex 20, France. stephanie.foulon@gmail.com.
Géric MauraDepartment of Studies in Public Health, French National Health Insurance, Paris, 75986, Cedex 20, France.
Marie DalichamptDepartment of Studies in Public Health, French National Health Insurance, Paris, 75986, Cedex 20, France.
François AllaGeneral Direction, French National Health Insurance, Paris, France.
Marc DebouverieDepartment of Neurology, Nancy University Hospital and Inserm CIC 1433, Nancy, France.
Thibault MoreauDepartment of Neurology, Dijon University Hospital, Dijon, France.
Alain WeillDepartment of Studies in Public Health, French National Health Insurance, Paris, 75986, Cedex 20, France.
Inserm · FRMaison des Sciences de l’Homme de Dijon · FRMutuelle Générale de l'Éducation Nationale · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data on the prevalence of multiple sclerosis (MS) in France are scarce. National and regional updated estimates are needed to better plan health policies. In this nationwide study, we provided estimates of the prevalence of MS in France in 2012 and mortality rate in 2013. MS cases were identified in the French national health insurance database (SNIIRAM-PMSI) using reimbursement data for disease-modifying treatment, long-term disease status for MS, disability pension for MS, and hospitalisation for MS (MS ICD-10 code: G35). We identified 99,123 MS cases, corresponding to an overall crude prevalence rate of 151.2 per 100,000 inhabitants [95% confidence interval (CI) 150.3-152.2]: 210.0 per 100,000 in women (95% CI 208.4-211.5) and 88.7 per 100,000 in men (95% CI 87.6-89.7). The overall prevalence rate was 155.6 per 100,000 inhabitants (95% CI 154.7-156.6) after standardization on the 2013-European population. We observed a prevalence gradient with a higher prevalence (190-200 per 100,000) in North-Eastern France and a lower prevalence in Southern and Western France (126-140). The crude mortality rate in 2013 was 13.7 per 1,000 MS cases (11.4 in women and 20.3 in men). The standardized mortality ratio was 2.56 (95% CI 2.41-2.72). Our results revise upwards the estimation of MS prevalence in France and confirm the excess mortality of MS patients compared to the general population.

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionAlgorithmsDatabases, FactualFemaleFranceHospitalizationHumansInsurance, HealthInternational Classification of DiseasesMaleMiddle AgedMultiple SclerosisEpidemiologyMortalityMultiple sclerosisPrevalence

Identifiers

PMID28516332
PMCPMC5486573
OpenAlexW2614460177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.