ArticleWorld journal of urology2017
"Finding the needle in a haystack": oncologic evaluation of patients treated for LUTS with holmium laser enucleation of the prostate (HoLEP) versus transurethral resection of the prostate (TURP).
Article in World journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Risk factors for incidental prostate cancer following surgery for benign prostatic enlargement: A systematic review and meta-analysis.Prostate cancer and prostatic diseases · 2026Pooled it
- Predictive factors of incidental prostate cancer in patients undergoing surgery for presumed benign prostatic hyperplasia: an updated systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- Incidence, predictive factors and oncological outcomes of incidental prostate cancer after endoscopic enucleation of the prostate: a systematic review and meta-analysis.World journal of urology · 2022Pooled it
- Prevalence and risk factors of incidental prostate cancer in certain surgeries for benign prostatic hyperplasia: A systematic review and meta-analysis.International braz j urol : official journal of the Brazilian Society of UrologyPooled it
- Rates of incidental prostate cancer following HoLEP Can it be predicted preoperatively?Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Article
- En Bloc Bipolar Prostate Enucleation Using the Mushroom Technique with Early Apical Release: Short-Term Outcomes.Medicina (Kaunas, Lithuania) · 2025Article
- A comparative analysis of robotic prostatectomy techniques post TURP/HOLEP: retzius-sparing vs. non-retzius approaches: evaluation of perioperative, functional, and oncological outcomes.International urology and nephrology · 2025Article
- Optimal PSA density threshold for prostate biopsy in benign prostatic obstruction patients with elevated PSA levels but negative MRI findings.BMC urology · 2025Article
- Incidental prostate cancer after holmium laser enucleation of the prostate: Critical analysis of independent risk factors and impact on surgical outcomes.BJUI compass · 2024Article
- Perioperative Rates of Incidental Prostate Cancer after Aquablation and Holmium Laser Enucleation of the Prostate.Urologia internationalis · 2024Article
- Review
- Relationships between holmium laser enucleation of the prostate and prostate cancer.Nature reviews. Urology · 2023Review
- The significance of the extent of tissue embedding for the detection of incidental prostate carcinoma on transurethral prostate resection material: the more, the better?Virchows Archiv : an international journal of pathology · 2022Article
- Is the systematic histological analysis of benign prostatic hyperplasia surgical specimen always necessary?International urology and nephrology · 2022Article
- Incidental prostate cancer after holmium laser enucleation of the prostate: incidence and predictive factors for clinical progression.International journal of clinical oncology · 2022Article
- Prevalence and risk factors for incidental prostate cancer in patients after transurethral resection of the prostate with negative results on prostate biopsy: A retrospective study.Investigative and clinical urology · 2022Article
- HoLEP after prostate biopsy: does it have any impact?World journal of urology · 2021Article
- Informative value of histological assessment of tissue acquired during aquablation of the prostate.World journal of urology · 2021Article
- The significance of a high preoperative PSA level for the detection of incidental prostate cancer in LUTS patients with large prostates.World journal of urology · 2021Article
- Comparative Study of the Effectiveness and Safety of Transurethral Bipolar Plasmakinetic Enucleation of the Prostate and Transurethral Bipolar Plasmakinetic Resection of the Prostate for Massive Benign Prostate Hyperplasia (>80 ml).Medical science monitor : international medical journal of experimental and clinical research · 2020Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate oncologic parameters of men with bothersome LUTS undergoing surgical treatment with HoLEP or TURP.
methodsFive hundred and eighteen patients undergoing HoLEP (n = 289) or TURP (n = 229) were retrospectively analyzed for total PSA, prostate volume, PSA density, history of prostate biopsy, resected prostate weight, and histopathological features. Univariate and multivariate logistic regression models were used to identify independent predictors of incidental PCa (iPCa).
resultsMen undergoing HoLEP had a significantly higher total PSA (median 5.5 vs. 2.3 ng/mL) and prostate volume (median 80 vs. 41 cc), and displayed a greater reduction of prostate volume after surgery compared to TURP patients (median 71 vs. 50%; all p < 0.001). With a prevalence of incidental PCa (iPCa) of 15 and 17% for HoLEP and TURP, respectively, the choice of procedure had no influence on the detection of iPCa (p = 0.593). However, a higher rate of false-negative preoperative prostate biopsies was noted among iPCa patients in the HoLEP arm (40 vs. 8%, p = 0.007). In multivariate logistic regression, we identified patient age (OR 1.04; 95% CI 1.01-1.07, p = 0.013) and PSA density (OR 2.13; 95% CI 1.09-4.18, p = 0.028) as independent predictors for the detection of iPCa.
conclusionsDespite differences in oncologic parameters, the choice of technique had no influence on the detection of iPCa. Increased patient age and higher PSA density were associated with iPCa. A higher rate of false-negative preoperative prostate biopsies was noted in HoLEP patients. Therefore, diagnostic assessment of LUTS patients requires a more adapted approach to exclude malignancy, especially in those with larger prostates.
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