Evidence map›Paper›PMID 28516265›Full record

ReviewReviews in endocrine & metabolic disorders2017

The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention.

Michael F Holick

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03496246 (Vitamin D Status in Inflammatory Bowel Disease), which is not on this map. Cited by 684 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
684citing papers in PubMed, 8 pooled it
74.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03496246 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Vitamin D Status in Inflammatory Bowel Disease

TypeinterventionalSponsorAssiut UniversityRan2018 to 2019Enrolled50ConditionsVitamin D Deficiency, Inflammatory Bowel DiseasesArmsserum total 25 hydroxycholecalciferol 25(OH) vitamin D, complete blood count (CBC), serum calcium level, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP)
3 · Its place in the literature

Who cites it

684 citing papers in PubMed, 8 syntheses or guidelines pooled it, 1,465 citations in OpenAlex.

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  11. Kinetics and concentrations of circulating 25-hydroxyvitamin D using different vitamin D repletion regimens.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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  18. Interaction between vitamin D and the growth hormone/insulin-like growth factor 1 axis in children: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
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624 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael F HolickEndocrinology, Nutrition and Diabetes, Department of Medicine, Boston University Medical Center, Boston, MA, 02118, USA. mfholick@bu.edu.
Boston University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D deficiency and insufficiency is a global health issue that afflicts more than one billion children and adults worldwide. The consequences of vitamin D deficiency cannot be under estimated. There has been an association of vitamin D deficiency with a myriad of acute and chronic illnesses including preeclampsia, childhood dental caries, periodontitis, autoimmune disorders, infectious diseases, cardiovascular disease, deadly cancers, type 2 diabetes and neurological disorders. This review is to put into perspective the controversy surrounding the definition for vitamin D deficiency and insufficiency as well as providing guidance for how to treat and prevent vitamin D deficiency.

Indexed as

AdultChildHumansNutrition AssessmentNutrition PolicyPandemicsRisk FactorsVitamin DVitamin D DeficiencyVitamin D25-hydroxyvitamin DRicketsSunlightVitamin D2Vitamin D3Vitamin D deficiencyVitamin D insufficiencyVitamin D toxicity

Identifiers

PMID28516265
OpenAlexW2616730536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.