Evidence map›Paper›PMID 28515867›Full record

ArticleEcology and evolution2017

The evolution of the major histocompatibility complex in upstream versus downstream river populations of the longnose dace.

Erika Crispo, Haley R Tunna, Noreen Hussain, Silvia S Rodriguez, Scott A Pavey, Leland J Jackson, Sean M Rogers

Open access · goldAbstract read
In one paragraph

Article in Ecology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Erika CrispoDepartment of Biological Sciences University of Calgary Calgary AB Canada.ORCID 0000-0002-9844-304X
Haley R TunnaDepartment of Biological Sciences University of Calgary Calgary AB Canada.
Noreen HussainDepartment of Biology Pace University New York NY USA.
Silvia S RodriguezDepartment of Biology Pace University New York NY USA.
Scott A PaveyUniversity of New Brunswick Saint John & Canadian Rivers Institute Saint John NB Canada.
Leland J JacksonDepartment of Biological Sciences University of Calgary Calgary AB Canada.
Sean M RogersDepartment of Biological Sciences University of Calgary Calgary AB Canada.ORCID 0000-0003-0851-8050
University of Calgary · CAPace University · USUniversity of New Brunswick · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Populations in upstream versus downstream river locations can be exposed to vastly different environmental and ecological conditions and can thus harbor different genetic resources due to selection and neutral processes. An interesting question is how upstream-downstream directionality in rivers affects the evolution of immune response genes. We used next-generation amplicon sequencing to identify eight alleles of the major histocompatibility complex (MHC) class II β exon 2 in the cyprinid longnose dace (

Indexed as

diversifying selectionheterozygote advantagemajor histocompatibility complexnegative frequency‐dependent selectionnext‐generation sequencingoverdominance

Identifiers

PMID28515867
PMCPMC5433983
OpenAlexW2604822059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.