ReviewNature reviews. Neuroscience2017
The sleep-deprived human brain.
Review in Nature reviews. Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05026541 (Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators), which is not on this map. Cited by 578 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators
Who cites it
578 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Pooled it
- Distinct Convergent Brain Alterations in Sleep Disorders and Sleep Deprivation: A Meta-Analysis.JAMA psychiatry · 2025Pooled it
- The influence of sleep on human taste function and perception: A systematic review.Journal of sleep research · 2025Pooled it
- Effect of music therapy on sleep quality in elderly: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Effects of physical exercise interventions on multidimensional health outcomes in patients with substance use disorders: a network meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Monitoring Daily Sleep, Mood, and Affect Using Digital Technologies and Wearables: A Systematic Review.Sensors (Basel, Switzerland) · 2024Pooled it
- European expert guidance on management of sleep onset insomnia and melatonin use in typically developing children.European journal of pediatrics · 2024Guideline
- Do subjective and objective baseline sleep disturbances predict post-traumatic stress disorder treatment response? A secondary analysis of a randomized controlled trial.European journal of psychotraumatology · 2026Trial
- Skin-attached bioadhesive patch enabling ultrasound deep brain stimulation and real-time electrophysiological monitoring for REM sleep enhancement.Nature communications · 2026Trial
- A digital mindfulness intervention improves sleep efficiency and heart rate variability in healthy adults.Scientific reports · 2026Trial
- REM sleep reduction leads to fear overgeneralization via negatively modulating prefrontal theta oscillations.BMC medicine · 2025Trial
- Medial parietal alpha-frequency transcranial alternating current stimulation for chronic insomnia: a randomized sham-controlled trial.Psychological medicine · 2025Trial
- Change in Sleep Latency as a Mediator of the Effect of Physical Activity Intervention on Executive Functions Among Children with ADHD: A Secondary Analysis from a Randomized Controlled Trial.Journal of autism and developmental disorders · 2024Trial
- Measuring the Impacts of Urbanicity and Different Exposome Factors on Human Brain through Exposure Network Mapping.Neuroscience bulletin · 2026Article
- Ubiquitin-conjugating Enzyme E2M Destabilizes Heat Shock Protein 70 and Mediates Sleep Deprivation-Induced Cognitive Impairment in Mice.Neurochemical research · 2026Article
- Acute Sleep Deprivation Is Associated with Altered F-Wave Temporal Dynamics and Nasalis Repetitive Nerve Stimulation Responses: A Paired Electrophysiological Study.Brain sciences · 2026Article
- Sleepiness During Night Shifts and Nurses' Self-Reported Cognitive Control, Cognitive Flexibility, and Handover Effectiveness: A Cross-Sectional Study.International nursing review · 2026Article
- Local autophagy impairment triggers brain-wide presynaptic remodeling and resilience.The EMBO journal · 2026Article
- Tilia Tomentosa promotes sleep, preserving sleep structure.Npj biological timing and sleep · 2026Article
- Protecting episodic memory after sleep loss: Similar benefits of exercise and naps via distinct neural contributions.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
518 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
How does a lack of sleep affect our brains? In contrast to the benefits of sleep, frameworks exploring the impact of sleep loss are relatively lacking. Importantly, the effects of sleep deprivation (SD) do not simply reflect the absence of sleep and the benefits attributed to it; rather, they reflect the consequences of several additional factors, including extended wakefulness. With a focus on neuroimaging studies, we review the consequences of SD on attention and working memory, positive and negative emotion, and hippocampal learning. We explore how this evidence informs our mechanistic understanding of the known changes in cognition and emotion associated with SD, and the insights it provides regarding clinical conditions associated with sleep disruption.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.