Evidence map›Paper›PMID 28515413›Full record

ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2018

Magnetic Susceptibility Changes in the Basal Ganglia and Brain Stem of Patients with Wilson's Disease: Evaluation with Quantitative Susceptibility Mapping.

Selim Doganay, Kazim Gumus, Gonca Koc, Ayse Kacar Bayram, Mehmet Sait Dogan, Duran Arslan, Hakan Gumus, Sureyya Burcu Gorkem, Saliha Ciraci, Halil Ibrahim Serin and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. [Reproducibility analysis of quantitative susceptibility mapping of cerebral subcortical nuclei in healthy adults].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
    Article
  9. Article
  10. Article
  11. [Present status of diagnosis and treatment of hepatolenticular degeneration].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019
    Article
  12. Six-year clinical and MRI quantitative susceptibility mapping (QSM) follow-up in neurological Wilson's disease under zinc therapy: a case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019
    Article
  13. Article
  14. Challenges and Recent Advances in Diagnosing Wilson Disease.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Selim DoganayPediatric Radiology, Faculty of Medicine, Erciyes University.
Kazim GumusBiomedical Imaging Research Center, Erciyes University.
Gonca KocPediatric Radiology, Faculty of Medicine, Erciyes University.
Ayse Kacar BayramPediatric Neurology, Faculty of Medicine, Erciyes University.
Mehmet Sait DoganPediatric Radiology, Faculty of Medicine, Erciyes University.
Duran ArslanPediatric Gastroenterology, Faculty of Medicine, Erciyes University.
Hakan GumusPediatric Neurology, Faculty of Medicine, Erciyes University.
Sureyya Burcu GorkemPediatric Radiology, Faculty of Medicine, Erciyes University.
Saliha CiraciPediatric Radiology, Faculty of Medicine, Erciyes University.
Halil Ibrahim SerinRadiology Department, Faculty of Medicine, Bozok University.
Abdulhakim CoskunPediatric Radiology, Faculty of Medicine, Erciyes University.
Erciyes University · TRBozok Universitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWilson's disease (WD) is characterized with the accumulation of copper in the liver and brain. The objective of this study is to quantitatively measure the susceptibility changes of basal ganglia and brain stem of pediatric patients with neurological WD using quantitative susceptibility mapping (QSM) in comparison to healthy controls.

methodsEleven patients with neurological WD (mean age 15 ± 3.3 years, range 10-22 years) and 14 agematched controls were prospectively recruited. Both groups were scanned on a 1.5 Tesla clinical scanner. In addition to T

resultsOne patient with WD had T

conclusionQSM method exhibits increased susceptibility differences of basal ganglia and brain stem in patients with WD that have neurologic impairment even if no signal alteration is detected on T

Indexed as

AdolescentAdultBasal GangliaBrain MappingBrain StemChildCopperFemaleHepatolenticular DegenerationHumansMagnetic Resonance ImagingMaleYoung AdultCoppercoppermagnetic resonance imagingquantitative susceptibility mappingWilson’s disease

Identifiers

PMID28515413
PMCPMC5760236
OpenAlexW2614421328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.