Evidence map›Paper›PMID 28515216›Full record

ArticleJournal of clinical microbiology2017

Assessment of the Cavidi ExaVir Load Assay for Monitoring Plasma Viral Load in HIV-2-Infected Patients.

Pedro Borrego, Maria Fátima Gonçalves, Perpétua Gomes, Lavínia Araújo, Inês Moranguinho, Inês Brito Figueiredo, Isabel Barahona, José Rocha, Claudino Mendonça, Maria Cesarina Cruz and 2 more

Open access · bronzeAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Pedro BorregoResearch Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal.
Maria Fátima GonçalvesLaboratório de Biologia Molecular, LMCBM, SPC, Centro Hospitalar Lisboa Ocidental-HEM, Lisbon, Portugal.
Perpétua GomesCentro de Investigação Interdisciplinar Egas Moniz, Instituto Superior de Ciências da Saúde Egas Moniz, Monte de Caparica, Portugal.
Lavínia AraújoResearch Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal.
Inês MoranguinhoResearch Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal.
Inês Brito FigueiredoResearch Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal.
Isabel BarahonaCentro de Investigação Interdisciplinar Egas Moniz, Instituto Superior de Ciências da Saúde Egas Moniz, Monte de Caparica, Portugal.
José RochaLaboratório ELISA, Hospital Agostinho Neto, Praia, Cabo Verde.
Claudino MendonçaLaboratório ELISA, Hospital Agostinho Neto, Praia, Cabo Verde.
Maria Cesarina CruzLaboratório de Análises Clínicas, Delegacia de Saúde, S. Vicente, Cabo Verde.
Jorge BarretoPrograma de Luta contra as Doenças de Transmissão Sexual, incluindo VIH/Sida, Ministério da Saúde e da Segurança Social, Praia, Cabo Verde.
Nuno TaveiraResearch Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal ntaveira@ff.ulisboa.pt.
University of Lisbon · PTCentro Hospitalar de Lisboa Ocidental · PTEscola Superior de Saúde Egas Moniz · PTMinistério da Saúde e da Segurança Social · CVUniversity of Cape Verde · CV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV plasma viral load is an established marker of disease progression and of response to antiretroviral therapy, but currently there is no commercial assay validated for the quantification of viral load in HIV-2-infected individuals. We sought to make the first clinical evaluation of Cavidi ExaVir Load (version 3) in HIV-2-infected patients. Samples were collected from a total of 102 individuals living in Cape Verde, and the HIV-2 viral load was quantified by both ExaVir Load and a reference in-house real-time quantitative PCR (qPCR) used in Portugal in 91 samples. The associations between viral load and clinical prognostic variables (CD4

Indexed as

AdolescentAdultAgedAged, 80 and overChildFemaleHIV-2HIV InfectionsHumansMaleMiddle AgedPlasmaPortugalViral LoadYoung AdultCape VerdeCavidi ExaVir loadHIV-2resource-limited settingsviral load assay

Identifiers

PMID28515216
PMCPMC5527414
OpenAlexW2614902832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.