Evidence map›Paper›PMID 28515196›Full record

Trial reportBMJ open2017

Cost-effectiveness of therapist-guided internet-delivered cognitive behaviour therapy for paediatric obsessive-compulsive disorder: results from a randomised controlled trial.

Fabian Lenhard, Richard Ssegonja, Erik Andersson, Inna Feldman, Christian Rück, David Mataix-Cols, Eva Serlachius

Erratum issued Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02191631 (Internet-delivered Cognitive Behavior Therapy for Adolescents With Obsessive-Compulsive Disorder), which is not on this map. Cited by 38 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 6 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02191631 nacompletednot on this map

Internet-delivered Cognitive Behavior Therapy for Adolescents With Obsessive-Compulsive Disorder: A Randomized Controlled Study

TypeinterventionalSponsorKarolinska InstitutetRan2014 to 2016Enrolled67ConditionsObsessive-Compulsive DisorderArmsInternet-delivered Cognitive Behavior Therapy
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 6 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Digital interventions in mental health: evidence syntheses and economic modelling.Health technology assessment (Winchester, England) · 2022
    Pooled it
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  6. Pooled it
  7. Trial
  8. Trial
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  10. Trial
  11. Trial
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Internet-Delivered Cognitive Behavioral Therapy for Anxiety.Advances in psychiatry and behavioral health · 2024
    Article
  18. Article
  19. The Cost of Obsessive-Compulsive Disorder in Swedish Youth.Child psychiatry and human development · 2023
    Article
  20. Review
4 · The record

Corrections and comments

  • Erratum issued
    2017
5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Fabian LenhardCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Richard SsegonjaDepartment of Women's and Children's Health (CHAP), Uppsala Universitet, Uppsala, Sweden.
Erik AnderssonCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Inna FeldmanDepartment of Women's and Children's Health (CHAP), Uppsala Universitet, Uppsala, Sweden.
Christian RückCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-8742-0168
David Mataix-ColsCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Eva SerlachiusCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Stockholm County Council · SEUppsala University · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the cost-effectiveness of a therapist-guided internet-delivered cognitive behaviour therapy (ICBT) intervention for adolescents with obsessive-compulsive disorder (OCD) compared with untreated patients on a waitlist.

designSingle-blinded randomised controlled trial.

settingA research clinic within the regular child and adolescent mental health service in Stockholm, Sweden.

participantsSixty-seven adolescents (12-17 years) with a Diagnostic and Statistical Manual of Mental Disorders Fifth Edition diagnosis of OCD.

interventionsEither a 12-week, therapist-guided ICBT intervention or a wait list condition of equal duration. PRIMARY OUTCOME MEASURES: Cost data were collected at baseline and after treatment, including healthcare use, supportive resources, prescription drugs, prescription-free drugs, school absence and productivity loss, as well as the cost of ICBT. Health outcomes were defined as treatment responder rate and quality-adjusted life years gain. Bootstrapped mixed model analyses were conducted comparing incremental costs and health outcomes between the groups from the societal and healthcare perspectives.

resultsCompared with waitlist control, ICBT generated substantial societal cost savings averaging US$-144.98 (95% CI -159.79 to -130.16) per patient. The cost reductions were mainly driven by reduced healthcare use in the ICBT group. From the societal perspective, the probability of ICBT being cost saving compared with waitlist control was approximately 60%. From the healthcare perspective, the cost per additional responder to ICBT compared with waitlist control was approximately US$78.

conclusionsThe results suggest that therapist-guided ICBT is a cost-effective treatment and results in societal cost savings, compared with patients who do not receive evidence-based treatment. Since, at present, most patients with OCD do not have access to evidence-based treatments, the results have important implications for the increasingly strained national and healthcare budgets. Future studies should compare the cost-effectiveness of ICBT with regular face-to-face CBT. TRIAL REGISTRATION NUMBER: NCT02191631.

Indexed as

Cost-Benefit AnalysisInternetAdolescentChildCognitive Behavioral TherapyFemaleHumansMaleObsessive-Compulsive DisorderQuality-Adjusted Life YearsSingle-Blind MethodSwedenTreatment Outcomecognitive behavior therapycost-effectivenessInternetObsessive-compulsive disorderpediatric

Identifiers

PMID28515196
PMCPMC5729979
OpenAlexW2614353674

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.