ArticleBMJ open2017
10-year trends in statin utilization in Taiwan: a retrospective study using Taiwan's National Health Insurance Research Database.
Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Clinical impact of pharmacogenetic risk variants in a large chinese cohort.Nature communications · 2025Article
- Interaction between influenza vaccine and statins affecting the risk of rhabdomyolysis in Taiwan: a nationwide case-centred analysis.EClinicalMedicine · 2025Article
- Statin Utilization for Primary Prevention of Cardiovascular Disease in Patients Developing First ST-Segment Elevation Myocardial Infarction: A Malaysian Retrospective Cohort Study.Health science reports · 2025Article
- Impact of Smoking on Overall and Cancer-Specific Mortality in Prostate Cancer: Elevated Risks in Older and Early-Stage Patients-A Population-Based Study.Life (Basel, Switzerland) · 2024Article
- Optimizing lipid control in Taiwanese diabetic patients: A collaborative consensus by the Diabetes Association of the Republic of China (Taiwan) and the Taiwanese Association of Diabetes Educators.Journal of diabetes investigation · 2024Article
- Evaluating atherogenic index of plasma as a predictor for metabolic syndrome: a cross-sectional analysis from Northern Taiwan.Frontiers in endocrinology · 2024Article
- Relationships between beliefs about statins and non-adherence in inpatients from Northwestern China: a cross-sectional survey.Frontiers in pharmacology · 2023Article
- National Trends in Statin Use in Lithuania from 2010 to 2021.Medicina (Kaunas, Lithuania) · 2022Article
- Trends in all-cause mortality and major causes of death between 2007 and 2018 among patients with diabetes in Taiwan.Frontiers in endocrinology · 2022Article
- Effect of introducing biologics to patients with rheumatoid arthritis on the risk of venous thromboembolism: a nationwide cohort study.Scientific reports · 2021Article
- The risk of major bleeding event in patients with chronic kidney disease on pentoxifylline treatment.Scientific reports · 2021Article
- Observational
- Paediatric computed tomography and subsequent risk of leukaemia, intracranial malignancy and lymphoma: a nationwide population-based cohort study.Scientific reports · 2020Article
- Time trends analysis of statin prescription prevalence, therapy initiation, dose intensity, and utilization from the hospital information system of Jinshan Hospital, Shanghai (2012-2018).BMC cardiovascular disorders · 2020Observational
- Lipid-lowering drug prescriptions in a group of Colombian patients.Biomedica : revista del Instituto Nacional de Salud · 2019Article
- Patterns of statin utilisation for new users and market dynamics in South Korea: a 13-year retrospective cohort study.BMJ open · 2019Article
- Statin use and Vital Organ Failure in Patients With Asthma-Chronic Obstructive Pulmonary Disease Overlap: A Time-Dependent Population-Based Study.Frontiers in pharmacology · 2019Article
- Statin for Tuberculosis and Pneumonia in Patients with Asthma⁻Chronic Pulmonary Disease Overlap Syndrome: A Time-Dependent Population-Based Cohort Study.Journal of clinical medicine · 2018Article
- Atorvastatin enhances radiosensitivity in hypoxia-induced prostate cancer cells related with HIF-1α inhibition.Bioscience reports · 2017Article
- Prior Use of Medication for Primary Prevention in Patients with Coronary Syndrome.Journal of primary care & community healthArticle
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3 authors.
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Abstract
objectiveStatins have been commonly used to treat patients with hypercholesterolaemia and to prevent cardiovascular disease (CVD) worldwide. This study examined trends in use of statins in Taiwan from 2002 to 2011.
designThis is a retrospective observational study focusing on the utilisation of statins.
settingThe monthly claims data for statins between 2002 and 2011 were retrieved from Taiwan's National Health Insurance Research Database.
main outcome measuresWe calculated the yearly prescription rate per new user for each statin. Products were classified as high-intensity/moderate-intensity/low-intensity statins by type of statin and dosage. Users were also classified based on disease histories.
resultsThe number of statin users increased from 10 299 (~1.4% of adults) in 2002 to 50 687 (~6.3% of adults) in 2011. Atorvastatin was the most commonly used agent (28.4%-36.7%) during the study period. After 2007, simvastatin ranked second with 21.7% market share, followed by rosuvastatin, a newer agent that exhibited a substantial growth in prescription rates (3.4% in 2005 and 19.5% in 2011). In 2011, 94.0% of new statin users used statin monotherapies, and 6.0% used combination therapies. Use of moderate-intensity statins increased from 49.0% in 2002 to 71.0% in 2011, while high-intensity statins remained low. Patients with history of coronary events or cerebrovascular events were more likely to be prescribed higher intensity statins compared with those without. Prescribing of higher intensity statins was not greater among people with diabetes compared with those without during 2007-2011. Selection of statins did not differ between people with versus without history of myopathy or liver injury.
conclusionAtorvastatin was the most commonly used statin in Taiwan during 2002-2011. While patients with history of CVD were more likely to be prescribed higher intensity statins compared with those without, this difference was not found comparing those with and without diabetes.
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