Evidence map›Paper›PMID 28515179›Full record

ArticleAmerican journal of physiology. Renal physiology2017

Arginase-2 mediates renal ischemia-reperfusion injury.

Wesley M Raup-Konsavage, Ting Gao, Timothy K Cooper, Sidney M Morris, W Brian Reeves, Alaa S Awad

RetractedOpen access · bronzeAbstract readRetracted Publication
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Role of tubular epithelial arginase-II in renal inflammaging.NPJ aging and mechanisms of disease · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Wesley M Raup-KonsavageDivision of Nephrology, Department of Medicine, College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania.
Ting GaoDivision of Nephrology, Department of Medicine, College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania.
Timothy K CooperDepartment of Comparative Medicine, College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania.
Sidney M MorrisDepartment of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania.
W Brian ReevesDepartment of Medicine, University of Texas Health Science Center San Antonio, San Antonio, Texas; and.
Alaa S AwadDivision of Nephrology, Department of Medicine, College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania; AwadA@uthscsa.edu.
Penn State Milton S. Hershey Medical Center · USPennsylvania State University · USThe University of Texas Health Science Center at San Antonio · USUniversity of Pittsburgh · US

Funding

Role of Arginase in Diabetic NephropathyR01DK094930 · NIDDK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI AWAD, ALAA S · 2012 to 2016
$1.9M
NIDDK NIH HHS R01 DK094930
6 · The paper itself

Abstract

Novel therapeutic interventions for preventing or attenuating kidney injury following ischemia-reperfusion injury (IRI) remain a focus of significant interest. Currently, there are no definitive therapeutic or preventive approaches available for ischemic acute kidney injury (AKI). Our objective is to determine

Indexed as

Acute Kidney InjuryAdenosine TriphosphateAnimalsArginaseBlood Urea NitrogenCreatinineKidneyMaleMice, Inbred C57BLMitochondriaNitric Oxide Synthase Type IIINitritesOxidative StressPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaReperfusion InjuryAdenosine TriphosphateArg2 protein, mouseArginaseCreatinineNitric Oxide Synthase Type IIINitritesNos3 protein, mousePeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, mousearginaseischemia-reperfusionmitochondrianitric oxide

Identifiers

PMID28515179
PMCPMC5582893
OpenAlexW2615110968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.