ArticleJournal of the American Heart Association2017
Antidepressants, Depression, and Venous Thromboembolism Risk: Large Prospective Study of UK Women.
Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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Who cites it
26 citing papers in PubMed, 59 citations in OpenAlex.
- Prescribed hormonal contraceptive use trends in the Estonian Biobank: A longitudinal observational study.PLoS medicine · 2026Observational
- Risk of venous thrombosis and pulmonary embolism in older in-patients with mental illness: systematic review.BJPsych bulletin · 2026Review
- Molecular regulatory mechanisms of depression-related thrombosis risk.Journal of medical biochemistry · 2025Article
- Association Between Antidepressant Use and Risk of Venous Thromboembolism: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Biomarkers and Mental Disorders: A Relevance Analysis Using a Random Forest Algorithm.Biomolecules · 2025Article
- The risk for psychiatric disorders in offspring from thrombosis-prone pedigrees in Sweden: a nationwide family study.Research and practice in thrombosis and haemostasis · 2025Article
- Anxiety and depression are associated with heightened risk of incident deep vein thrombosis: Mediation through stress-related neural mechanisms.American journal of hematology · 2024Article
- Complications and Healthcare Cost of Total Hip Arthroplasty in Patients with Depressive Disorder.Hip & pelvis · 2024Article
- Dispensed prescription medications and short-term risk of pulmonary embolism in Norway and Sweden.Scientific reports · 2024Article
- Sex-specific differences in the clinical profile among psychiatric patients with pulmonary Embolism: a hospital-based retrospective study.BMC pulmonary medicine · 2024Article
- Causal association between major depressive disorder and venous thromboembolism: a bidirectional mendelian randomization study.Frontiers in genetics · 2024Article
- Clinical Characteristics of Asymptomatic Thromboembolism in Psychiatric Inpatients: A Retrospective Study.Neuropsychiatric disease and treatment · 2024Article
- Circulating metabolites modulated by diet are associated with depression.Molecular psychiatry · 2023Article
- Article
- Pulmonary Embolism After in vitro Fertilization and Cesarean Section: Two Case Reports and Brief Review of the Literature.International journal of women's health · 2022Article
- Serotonin: a platelet hormone modulating cardiovascular disease.Journal of thrombosis and thrombolysis · 2021Review
- The Usefulness of the Combination of D-Dimer and Soluble Fibrin Monomer Complex for Diagnosis of Venous Thromboembolism in Psychiatric Practice: A Prospective Study.Vascular health and risk management · 2021Article
- COVID-19 quarantine and acute pulmonary embolism.Revista espanola de cardiologia (English ed.) · 2020Article
- [COVID-19 quarantine and acute pulmonary embolism].Revista espanola de cardiologia · 2020Article
- Pediatric Massive and Submassive Pulmonary Embolism: A Single-Center Experience.Hospital pediatrics · 2020Article
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundSome investigators have reported an excess risk of venous thromboembolism (VTE) associated with depression and with use of antidepressant drugs. We explored these associations in a large prospective study of UK women. METHODS AND
resultsThe Million Women Study recruited 1.3 million women through the National Health Service Breast Screening Programme in England and Scotland. Three years after recruitment, women were sent a second questionnaire that enquired about depression and regular use of medications in the previous 4 weeks. The present analysis included those who responded and did not have prior VTE, cancer, or recent surgery. Follow-up for VTE was through linkage to routinely collected National Health Service statistics. Cox regression analyses yielded adjusted hazard ratios and 95% CIs. A total of 734 092 women (mean age 59.9 years) were included in the analysis; 6.9% reported use of antidepressants, 2.7% reported use of other psychotropic drugs, and 1.8% reported being treated for depression or anxiety but not use of psychotropic drugs. During follow-up for an average of 7.3 years
conclusionsUse of antidepressants is common in UK women and is associated with an increased risk of VTE.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.