Evidence map›Paper›PMID 28515081›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2017

Flexible ammonia handling strategies using both cutaneous and branchial epithelia in the highly ammonia-tolerant Pacific hagfish.

Alexander M Clifford, Alyssa M Weinrauch, Susan L Edwards, Michael P Wilkie, Greg G Goss

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. The importance of a single amino acid substitution in reduced red blood cell carbonic anhydrase function of early-diverging fish.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2020
    Article
  3. Article
  4. Dropping the base: recovery from extreme hypercarbia in the COJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2018
    Article
  5. Post-prandial physiology and intestinal morphology of the Pacific hagfish (Eptatretus stoutii).Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2018
    Article
  6. Heads you gain, tails you lose.American journal of physiology. Regulatory, integrative and comparative physiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alexander M CliffordDepartment of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada; alex.clifford@ualberta.ca.
Alyssa M WeinrauchDepartment of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.ORCID http://orcid.org/0000-0001-5710-0035
Susan L EdwardsBamfield Marine Sciences Centre, Bamfield, British Columbia, Canada.
Michael P WilkieBamfield Marine Sciences Centre, Bamfield, British Columbia, Canada.
Greg G GossDepartment of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.
University of Alberta · CABamfield Marine Sciences Centre · CA

Funding

The Maine Biomedical Research Network (INBRE)P20GM103423 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI Dustin Lynn Updike · 2012 to 2026
$60.0M
NIGMS NIH HHS P20 GM103423
6 · The paper itself

Abstract

Hagfish consume carrion, potentially exposing them to hypoxia, hypercapnia, and high environmental ammonia (HEA). We investigated branchial and cutaneous ammonia handling strategies by which Pacific hagfish (

Indexed as

Adaptation, PhysiologicalAmmoniaAnimalsCutaneous EliminationDrug ToleranceEpitheliumGillsHagfishesSkinAmmoniaagnathacyclostomenitrogenrhesus glycoproteinskin

Identifiers

PMID28515081
PMCPMC5582951
OpenAlexW2616551113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.