Evidence map›Paper›PMID 28515048›Full record

ArticleG3 (Bethesda, Md.)2017

Essential Function of the Serine Hydroxymethyl Transferase (SHMT) Gene During Rapid Syncytial Cell Cycles in

Franziska Winkler, Maria Kriebel, Michaela Clever, Stephanie Gröning, Jörg Großhans

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
  5. Article
  6. The Expression ofCells · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Comparative proteomics analysis of adultFrontiers in cellular and infection microbiology · 2023
    Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Activating embryonic development in Drosophila.Seminars in cell & developmental biology · 2018
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Franziska WinklerInstitute for Developmental Biochemistry, Medical School, University of Göttingen, 37077, Germany.
Maria KriebelInstitute for Developmental Biochemistry, Medical School, University of Göttingen, 37077, Germany.
Michaela CleverInstitute for Developmental Biochemistry, Medical School, University of Göttingen, 37077, Germany.
Stephanie GröningInstitute for Developmental Biochemistry, Medical School, University of Göttingen, 37077, Germany.
Jörg GroßhansInstitute for Developmental Biochemistry, Medical School, University of Göttingen, 37077, Germany jgrossh@gwdg.de.ORCID 0000-0003-1114-9233
University of Göttingen · DE

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
NIH HHS P40 OD010949NIH HHS P40 OD018537
6 · The paper itself

Abstract

Many metabolic enzymes are evolutionarily highly conserved and serve a central function in the catabolism and anabolism of cells. The serine hydroxymethyl transferase (SHMT) catalyzing the conversion of serine and glycine and vice versa feeds into tetrahydrofolate (THF)-mediated C1 metabolism. We identified a

Indexed as

MutationAnimalsDrosophila melanogasterEmbryo, NonmammalianGiant CellsGlycine HydroxymethyltransferaseInterphaseGlycine Hydroxymethyltransferasecell cycleDrosophilametabolismmidblastula transitionserine hydroxymethyl transferase

Identifiers

PMID28515048
PMCPMC5499137
OpenAlexW2615455054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.