Evidence map›Paper›PMID 28514967›Full record

ArticleBMC cardiovascular disorders2017

AT

Kristoffer Bernhem, Kalaiselvan Krishnan, Alexander Bondar, Hjalmar Brismar, Anita Aperia, Lena Scott

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Kristoffer BernhemScience for Life Laboratory, Department of Applied Physics, Royal Institute of Technology, Stockholm, Sweden.
Kalaiselvan KrishnanScience for Life Laboratory, Department of Applied Physics, Royal Institute of Technology, Stockholm, Sweden.
Alexander BondarInstitute of Chemical Biology and Fundamental Medicine, 630090, Novosibirsk, Russia.
Hjalmar BrismarScience for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, PO Box 1031, 17121, Solna, Sweden.
Anita AperiaScience for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, PO Box 1031, 17121, Solna, Sweden. anita.aperia@ki.se.
Lena ScottScience for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, PO Box 1031, 17121, Solna, Sweden.
Science for Life Laboratory · SEInstitute of Chemical Biology and Fundamental Medicine · RUKTH Royal Institute of Technology · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlockers of angiotensin II type 1 receptor (AT

methodsTo elucidate these questions, we have studied the Ca

resultsRepeated exposure to pharmacological (100 nM) concentrations of AngII caused, as expected, a down-regulation of the Ca

conclusionsOur findings have implications for the understanding of hyperactivity of the angiotensin system and for use of Ca

Indexed as

Angiotensin IIAnimalsAnimals, NewbornCalcium Channel BlockersCalcium Channels, L-TypeCalcium SignalingDose-Response Relationship, DrugHEK293 CellsHumansMuscle, Smooth, VascularMyocytes, CardiacMyocytes, Smooth MuscleNifedipineRats, Sprague-DawleyReceptor, Angiotensin, Type 1Time FactorsAGTR1 protein, humanAngiotensin IICACNA1C protein, humanCacna1c protein, ratCalcium Channel BlockersCalcium Channels, L-TypeL-type calcium channel alpha(1C)NifedipineReceptor, Angiotensin, Type 1TRPC Cation ChannelsVerapamilAT1RCalciumCell imaginghypertensionVGCC

Identifiers

PMID28514967
PMCPMC5436436
OpenAlexW2616402949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.