Evidence map›Paper›PMID 2851484›Full record

ArticleGenetics1988

Transposon tagging using Ty elements in yeast.

D J Garfinkel, M F Mastrangelo, N J Sanders, B K Shafer, J N Strathern

Abstract read
In one paragraph

Article in Genetics, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. RNAi in budding yeast.Science (New York, N.Y.) · 2009
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Mammalian germ-line transgenesis by transposition.Proceedings of the National Academy of Sciences of the United States of America · 2002
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

D J GarfinkelBionetics Research, Inc., National Cancer Institute-Frederick Cancer Research Facility, Maryland 21701.
M F Mastrangelo
N J Sanders
B K Shafer
J N Strathern

Funding

PROVIDE BASIC CANCER RESEARCHN01CO074101 · CO · ADVANCED BIOSCIENCE LABORATORIES, INC. · PI VANDE WOUDE, GEORGE F · 1987 to 1994
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NCI NIH HHS N01-CO-74101
6 · The paper itself

Abstract

We have used the ability to induce high levels of Ty transposition to develop a method for transposon mutagenesis in Saccharomyces cerevisiae. To facilitate genetic and molecular analysis, we have constructed GAL1-promoted TyH3 or Ty917 elements that contain unique cloning sites, and marked these elements with selectable genes. These genes include the yeast HIS3 gene, and the plasmid PiAN7 containing the Tn903 NEO gene. The marked Ty elements retain their ability to transpose, to mutate the LYS2, LYS5, or STE2 genes, and to activate the promoterless his3 delta 4 target gene. Ty elements containing selectable genes are also useful in strain construction, in chromosomal mapping, and in gene cloning strategies.

Indexed as

Cloning, MolecularDNA Transposable ElementsMutationCrosses, GeneticGenes, FungalGenotypeNucleic Acid HybridizationPlasmidsSaccharomyces cerevisiaeDNA Transposable Elements

Identifiers

PMID2851484
PMCPMC1203510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.