Evidence map›Paper›PMID 28514659›Full record

ArticleCell reports2017

The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands.

Hugo G Hilton, Curtis P McMurtrey, Alex S Han, Zakia Djaoud, Lisbeth A Guethlein, Jeroen H Blokhuis, Jason L Pugh, Ana Goyos, Amir Horowitz, Rico Buchli and 10 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
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  15. Genetic gateways to COVID-19 infection: Implications for risk, severity, and outcomes.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Review
  16. Review
  17. Article
  18. Observational
  19. Article
  20. The C-terminal extension landscape of naturally presented HLA-I ligands.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 3 countries.

Hugo G HiltonDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Microbiology & Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA. Electronic address: hghhilton@gmail.com.
Curtis P McMurtreyDepartment of Microbiology & Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Alex S HanDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Microbiology & Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Zakia DjaoudDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Microbiology & Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Lisbeth A GuethleinDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Microbiology & Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Jeroen H BlokhuisDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Microbiology & Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Jason L PughDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Microbiology & Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Ana GoyosDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Microbiology & Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Amir HorowitzDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Microbiology & Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Rico BuchliPure Protein LLC, Oklahoma City, OK 73104, USA.
Ken W JacksonDepartment of Microbiology & Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Wilfred BardetDepartment of Microbiology & Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
David A BushnellDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Philip J RobinsonDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Juan L MendozaDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Molecular & Cellular Physiology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Michael E BirnbaumDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Molecular & Cellular Physiology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Morten NielsenDepartment of Bio and Health Informatics, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark; Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, Buenos Aires, Argentina.
K Christopher GarciaDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Molecular & Cellular Physiology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
William H HildebrandDepartment of Microbiology & Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Peter ParhamDepartment of Structural Biology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Microbiology & Immunology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Stanford University · USUniversity of Oklahoma Health Sciences Center · USPure Protein (United States) · USTechnical University of Denmark · DK

Funding

Using a tonsil organoid system to probe conditions for the induction of protective antibody and T cell responses to influenza.U19AI057229 · NIAID · STANFORD UNIVERSITY · PI Mark Morris Davis · 2003 to 2026
$88.5M
MOLECULAR &CELLULAR IMMUNOBIOLOGYT32AI007290 · NIAID · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Olivia M Martinez · 1985 to 2026
$27.0M
GENETICS TRAINING PROGRAM FOR PHD CANDIDATEST32GM007790 · NIGMS · STANFORD UNIVERSITY · PI BRUNET, ANNE, KINGSLEY, DAVID M · 1985 to 2020
$12.8M
Structural correlates of T cell receptor signalingR01AI103867 · NIAID · STANFORD UNIVERSITY · PI Kenan Christopher GARCIA · 2014 to 2026
$5.3M
INTERACTIONS BETWEEN HLA CLASS I &CYTOLYTIC LYMPHOCYTESR01AI022039 · NIAID · STANFORD UNIVERSITY · PI PARHAM, PETER R · 1985 to 2017
$5.2M
Diversifying interferon functions through combinatorial and structural biologyK01CA175127 · NCI · STANFORD UNIVERSITY · PI MENDOZA, JUAN LUIS · 2013 to 2017
$584k
NCI NIH HHS K01 CA175127NIAID NIH HHS R01 AI022039NIAID NIH HHS R01 AI103867NIAID NIH HHS T32 AI007290NIAID NIH HHS U19 AI057229NIGMS NIH HHS T32 GM007790
6 · The paper itself

Abstract

HLA-B

Indexed as

Amino Acid MotifsCytotoxicity, ImmunologicHLA-B AntigensHLA-C AntigensHumansKiller Cells, NaturalLigandsModels, BiologicalPeptidesProtein BindingProteomeReceptors, KIR2DL3Recombination, GeneticHLA-B46 antigenHLA-B AntigensHLA-C AntigensLigandsPeptidesProteomeReceptors, KIR2DL3antigen presentationgenetic polymorphismHLA class Ihost-pathogen interactionsKIRmass spectrometrymodern human migrationpeptidome

Identifiers

PMID28514659
PMCPMC5510751
OpenAlexW2615034605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.