ArticleNature chemical biology2017
Small-molecule pheromones and hormones controlling nematode development.
Article in Nature chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed.
- Cytochrome P450-mediated regulation of pheromone biosynthesis and adult emergence in Monochamus saltuarius (Coleoptera, Cerambycidae), with implications for pest management.Pest management science · 2026Article
- Expression, purification, and in vitro characterization of the carboxylesterase CEST-9.2 from Caenorhabditis elegans.Bioscience reports · 2026Article
- O-acyltransferase genes involved in the production of volatile sex pheromones inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
- Nictation behavior in nematodes.BMC biology · 2025Review
- Biosynthesis of modular signaling molecules requires functional diversification of carboxylesterases in Pristionchus pacificus.Communications biology · 2025Article
- Nematode Pheromones as Key Mediators of Behavior, Development, and Ecological Interactions.Biomolecules · 2025Review
- High Nutritional Conditions Influence Feeding Plasticity in Pristionchus pacificus and Render Worms Non-Predatory.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025Article
- Discovery of a parallel family of euglenatide analogs in Euglena gracilis.Natural products and bioprospecting · 2025Article
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting.Nature microbiology · 2024Article
- Anti-Aging Effect ofInternational journal of molecular sciences · 2024Article
- APEX: an Annotation Propagation Workflow through Multiple Experimental Networks to Improve the Annotation of New Metabolite Classes inAnalytical chemistry · 2023Article
- Semantic Representation of Neural Circuit Knowledge inbioRxiv : the preprint server for biology · 2023Article
- Natural genetic variation in the pheromone production ofProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Repurposing degradation pathways for modular metabolite biosynthesis in nematodes.Nature chemical biology · 2023Review
- Nematode Pheromones: Structures and Functions.Molecules (Basel, Switzerland) · 2023Review
- Chemical Signaling Regulates Axon Regeneration via the GPCR-Gqα Pathway inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- On the role of dauer in the adaptation of nematodes to a parasitic lifestyle.Parasites & vectors · 2021Review
- CREB mediates the C. elegans dauer polyphenism through direct and cell-autonomous regulation of TGF-β expression.PLoS genetics · 2021Article
- Nematode Signaling Molecules Are Extensively Metabolized by Animals, Plants, and Microorganisms.ACS chemical biology · 2021Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
The existence of small-molecule signals that influence development in Caenorhabditis elegans has been known for several decades, but only in recent years have the chemical structures of several of these signals been established. The identification of these signals has enabled connections to be made between these small molecules and fundamental signaling pathways in C. elegans that influence not only development but also metabolism, fertility, and lifespan. Spurred by these important discoveries and aided by recent advances in comparative metabolomics and NMR spectroscopy, the field of nematode chemistry has the potential to expand dramatically in the coming years. This Perspective will focus on small-molecule pheromones and hormones that influence developmental events in the nematode life cycle (ascarosides, dafachronic acids, and nemamides), will cover more recent work regarding the biosynthesis of these signals, and will explore how the discovery of these signals is transforming our understanding of nematode development and physiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.