Evidence map›Paper›PMID 28514193›Full record

ArticleAIDS patient care and STDs2017

90-90-90-Plus: Maintaining Adherence to Antiretroviral Therapies.

Inge B Corless, Alex J Hoyt, Lynda Tyer-Viola, Elizabeth Sefcik, Jeanne Kemppainen, William L Holzemer, Lucille Sanzero Eller, Kathleen Nokes, J Craig Phillips, Carol Dawson-Rose and 13 more

Abstract read
In one paragraph

Article in AIDS patient care and STDs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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  8. Observational
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  13. Review
  14. Determination of a cutoff value for medication regimen complexity index to predict polypharmacy in HIV+ older patient.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2019
    Observational
  15. Barriers and Facilitators for Antiretroviral Treatment Adherence Among HIV-Positive African American and Latino Men Who Have Sex With Men.AIDS education and prevention : official publication of the International Society for AIDS Education · 2019
    Article
  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Inge B Corless1 MGH Institute of Health Professions School of Nursing , Boston, Massachusetts.
Alex J Hoyt1 MGH Institute of Health Professions School of Nursing , Boston, Massachusetts.
Lynda Tyer-Viola2 Texas Children's Pavillion for Women , Houston, Texas.
Elizabeth Sefcik3 Texas A&M University-Corpus Christi , Corpus Christi, Texas.
Jeanne Kemppainen4 University of North Carolina-Wilmington School of Nursing , Wilmington, North Carolina.
William L Holzemer5 Rutgers College of Nursing , Newark, New Jersey.
Lucille Sanzero Eller5 Rutgers College of Nursing , Newark, New Jersey.
Kathleen Nokes6 Hunter-Bellevue School of Nursing , CUNY, New York, New York.
J Craig Phillips7 University of Ottawa , Ottawa, Canada .
Carol Dawson-Rose8 UCSF School of Nursing , San Francisco, California.
Marta Rivero-Mendez9 University of Puerto Rico , San Juan, Puerto Rico .
Scholastika Iipinge10 University of Namibia , Windhoek, Namibia .
Puangtip Chaiphibalsarisdi11 Faculty of Nursing, Saint Louis College , Bangkok, Thailand .
Carmen J Portillo8 UCSF School of Nursing , San Francisco, California.
Wei-Ti Chen12 School of Nursing, Yale University , New Haven, Connecticut.
Allison R Webel13 Bolton School of Nursing, Case Western University , Cleveland, Ohio.
John Brion14 College of Nursing, The Ohio State University , Columbus, Ohio.
Mallory O Johnson15 UCSF , San Francisco, California.
Joachim Voss13 Bolton School of Nursing, Case Western University , Cleveland, Ohio.
Mary Jane Hamilton16 Texas A&M University-Corpus Christi , Corpus Christi, Texas.
Kathleen M Sullivan17 University of Hawaii School of Nursing , Honolulu, Hawaii.
Kenn M Kirksey18 Harris Health System , Houston, Texas.
Patrice K Nicholas1 MGH Institute of Health Professions School of Nursing , Boston, Massachusetts.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
NCATS NIH HHS UL1 TR001863NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

Medication adherence is the "Plus" in the global challenge to have 90% of HIV-infected individuals tested, 90% of those who are HIV positive treated, and 90% of those treated achieve an undetectable viral load. The latter indicates viral suppression, the goal for clinicians treating people living with HIV (PLWH). The comparative importance of different psychosocial scales in predicting the level of antiretroviral adherence, however, has been little studied. Using data from a cross-sectional study of medication adherence with an international convenience sample of 1811 PLWH, we categorized respondent medication adherence as None (0%), Low (1-60%), Moderate (61-94%), and High (95-100%) adherence based on self-report. The survey contained 13 psychosocial scales/indices, all of which were correlated with one another (p < 0.05 or less) and had differing degrees of association with the levels of adherence. Controlling for the influence of race, gender, education, and ability to pay for care, all scales/indices were associated with adherence, with the exception of Berger's perceived stigma scale. Using forward selection stepwise regression, we found that adherence self-efficacy, depression, stressful life events, and perceived stigma were significant predictors of medication adherence. Among the demographic variables entered into the model, nonwhite race was associated with double the odds of being in the None rather than in the High adherence category, suggesting these individuals may require additional support. In addition, asking about self-efficacy, depression, stigma, and stressful life events also will be beneficial in identifying patients requiring greater adherence support. This support is essential to medication adherence, the Plus to 90-90-90.

Indexed as

Social StigmaAdultAnti-HIV AgentsCross-Sectional StudiesDepressionDrug MonitoringFemaleHIV InfectionsHumansLife Change EventsLogistic ModelsMaleMedication AdherenceMiddle AgedSelf EfficacySelf ReportAnti-HIV Agents90-90-90adherenceARTpredictors

Identifiers

PMID28514193
PMCPMC5446604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.