Evidence map›Paper›PMID 28514062›Full record

ArticleCancer science2017

Locoregional therapy with α-emitting trastuzumab against peritoneal metastasis of human epidermal growth factor receptor 2-positive gastric cancer in mice.

Huizi Keiko Li, Yukie Morokoshi, Kotaro Nagatsu, Tadashi Kamada, Sumitaka Hasegawa

Open access · goldAbstract readComparative Study
In one paragraph

Article in Cancer science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 44 citations in OpenAlex.

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  11. Utility ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
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  14. Radioimmunotherapy with anCancer science · 2021
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  15. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
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  16. Enhancement ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
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  17. Article
  18. Evidence of Local Concentration of α-Particles fromJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
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  19. Chemical science · 2019
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  20. ImprovingInternational journal of nanomedicine · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Huizi Keiko LiRadiation and Cancer Biology Team, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Yukie MorokoshiRadiation and Cancer Biology Team, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Kotaro NagatsuTargetry and Target Chemistry Team, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Tadashi KamadaGraduate School of Medical and Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Sumitaka HasegawaRadiation and Cancer Biology Team, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.ORCID http://orcid.org/0000-0002-7793-9759
National Institutes for Quantum Science and Technology · JPChiba University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peritoneal metastasis of gastric cancer (PMGC) is incurable and thus has an extremely poor prognosis. We have found, however, that locoregionally administered trastuzumab armed with astatine-211 (

Indexed as

Administration, IntravenousAnimalsAstatineCell Line, TumorErb-b2 Receptor Tyrosine KinasesHumansInjections, IntraperitonealMicePeritoneal NeoplasmsRadioimmunotherapyRadiopharmaceuticalsStomach NeoplasmsTissue DistributionTrastuzumabTreatment OutcomeXenograft Model Antitumor AssaysAstatineERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesRadiopharmaceuticalsTrastuzumabgastric cancerperitoneal metastasisradioimmunotherapytrastuzumabα-Particle

Identifiers

PMID28514062
PMCPMC5543454
OpenAlexW2614937124

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.