Evidence map›Paper›PMID 28513546›Full record

ReviewInternational journal of molecular sciences2017

Edible Plants and Their Influence on the Gut Microbiome and Acne.

Ashley K Clark, Kelly N Haas, Raja K Sivamani

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Gut microbiota and psoriasis: pathogenesis, targeted therapy, and future directions.Frontiers in cellular and infection microbiology · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Characterization ofMicroorganisms · 2021
    Article
  11. Review
  12. Article
  13. The Skin Microbiome: A New Actor in Inflammatory Acne.American journal of clinical dermatology · 2020
    Review
  14. Review
  15. Article
  16. The influence of exposome on acne.Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Review
  17. Numerical analyses of intestinal microbiota by data mining.Journal of clinical biochemistry and nutrition · 2018
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ashley K ClarkSchool of Medicine, University of California-Davis, Sacramento, CA 95816, USA. akclark@ucdavis.edu.
Kelly N HaasDepartment of Dermatology, University of California-Davis, Sacramento, CA 95816, USA. kelly.nicole.haas@gmail.com.
Raja K SivamaniDepartment of Dermatology, University of California-Davis, Sacramento, CA 95816, USA. raja.sivamani.md@gmail.com.
University of California, Davis · USCalifornia State University, Sacramento · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
UC Davis CTSC TL1 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility MentorshipTL1TR001861 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MEDICI, VALENTINA · 2016 to 2025
$4.7M
NCATS NIH HHS TL1 TR001861NCATS NIH HHS UL1 TR001860
6 · The paper itself

Abstract

Acne vulgaris affects most people at some point in their lives. Due to unclear etiology, likely with multiple factors, targeted and low-risk treatments have yet to be developed. In this review, we explore the multiple causes of acne and how plant-based foods and supplements can control these. The proposed causative factors include insulin resistance, sex hormone imbalances, inflammation and microbial dysbiosis. There is an emerging body of work on the human gut microbiome and how it mediates feedback between the foods we eat and our bodies. The gut microbiome is also an important mediator of inflammation in the gut and systemically. A low-glycemic load diet, one rich in plant fibers and low in processed foods, has been linked to an improvement in acne, possibly through gut changes or attenuation of insulin levels. Though there is much interest in the human microbiome, there is much more unknown, especially along the gut-skin axis. Collectively, the evidence suggests that approaches such as plant-based foods and supplements may be a viable alternative to the current first line standard of care for moderate acne, which typically includes antibiotics. Though patient compliance with major dietary changes is likely much lower than with medications, it is a treatment avenue that warrants further study and development.

Indexed as

Dietary SupplementsGastrointestinal MicrobiomePlants, EdibleAcne VulgarisHumansProbioticsSkinSkin Physiological Phenomenaacnebotanicalsgastrointestinal tractinsulin resistancemicrobiotapolyphenolsprobioticsskin

Identifiers

PMID28513546
PMCPMC5454980
OpenAlexW2616117803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.