Evidence map›Paper›PMID 28512585›Full record

ReviewNeural plasticity2017

Understanding the Mechanisms of Recovery and/or Compensation following Injury.

Michael J Hylin, Abigail L Kerr, Ryan Holden

Registry-linked trialAbstract readReview
In one paragraph

Review in Neural plasticity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04429945 (Immersive Virtual Reality to Improve Outcomes in Patients With Stroke), which is not on this map. Cited by 50 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04429945 nacompletednot on this mapstarted 2021, after this paper: background citation

Immersive Virtual Reality to Improve Outcomes in Patients With Stroke: A Pilot Study

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2021 to 2022Enrolled10ConditionsStrokeArmsVirtual Reality
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael J HylinNeurotrauma and Rehabilitation Laboratory, Department of Psychology, Southern Illinois University, Carbondale, IL, USA.ORCID 0000-0002-8600-3047
Abigail L KerrDepartment of Psychology, Illinois Wesleyan University, Bloomington, IL, USA.
Ryan HoldenNeurotrauma and Rehabilitation Laboratory, Department of Psychology, Southern Illinois University, Carbondale, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Injury due to stroke and traumatic brain injury result in significant long-term effects upon behavioral functioning. One central question to rehabilitation research is whether the nature of behavioral improvement observed is due to recovery or the development of compensatory mechanisms. The nature of functional improvement can be viewed from the perspective of behavioral changes or changes in neuroanatomical plasticity that follows. Research suggests that these changes correspond to each other in a bidirectional manner. Mechanisms surrounding phenomena like neural plasticity may offer an opportunity to explain how variables such as experience can impact improvement and influence the definition of recovery. What is more, the intensity of the rehabilitative experiences may influence the ability to recover function and support functional improvement of behavior. All of this impacts how researchers, clinicians, and medical professionals utilize rehabilitation.

Indexed as

Neuronal PlasticityRecovery of FunctionStroke RehabilitationAnimalsBehavior, AnimalBrainBrain Injuries, TraumaticHumansStroke

Identifiers

PMID28512585
PMCPMC5415868

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.