Evidence map›Paper›PMID 28512490›Full record

ArticleIranian endodontic journal2017

Maryam Javidi, Parisa Dastmalchi, Mina Zarei, Maryam Shayani Rad, Ahmad Ghorbani

Abstract read
In one paragraph

Article in Iranian endodontic journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Effect of incorporation of triphala into AH26 sealer on its cytotoxicity at different intervals.Journal of dental research, dental clinics, dental prospects · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maryam JavidiDental Materials Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran.
Parisa DastmalchiDental Materials Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran.
Mina ZareiDental Materials Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran.
Maryam Shayani RadStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
Ahmad GhorbaniPharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this METHODS AND MATERIALS: The Pulpdent, AH-26, and NZOE sealers were prepared and exposed to cell culture media immediately after setting, and 24 h and one week after setting. Then, the primary cultured HGFs were incubated for 24 h with different dilutions (1:1 to 1:32) of each sealer extract. Cell viability was evaluated by methyl thiazolyl diphenyl tetrazolium bromide (MTT) assay. The results were compared using two-way analysis of variance followed by Tukey's post hoc test. The level of significance was set at 0.05.

resultsAll sealer extracts, up to 32 times dilutions, showed cytotoxicity when exposed to HGF immediately after setting. The extracts obtained 24 h or one week after setting showed lower cytotoxicity than extracts obtained immediately after setting. At all setting times, NZOE showed lower cytotoxicity than Pulpdent and AH-26. While one-week extracts of NZOE had no significant effect on the viability of HGF at dilutions 1:4 to 1:32, both Pulpdent and AH-26 decreased the cell viability at dilutions of 1:4 and 1:8.

conclusionNZOE exhibited lower cytotoxicity compared to Pulpdent and AH-26 on HGF and has the potential to be considered as a new root canal filling material.

Indexed as

CytotoxicityHuman Gingival FibroblastMTT assayNanoSealer

Identifiers

PMID28512490
PMCPMC5431722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.