Evidence map›Paper›PMID 28512446›Full record

ArticleFrontiers in neurology2017

Neuroprotective Roles of l-Cysteine in Attenuating Early Brain Injury and Improving Synaptic Density

Tong Li, Lingxiao Wang, Quan Hu, Song Liu, Xuemei Bai, Yunkai Xie, Tiantian Zhang, Shishi Bo, Xiangqian Gao, Shuhua Wu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Brain-Derived Cystathionine β-Synthase-Generated HCurrent issues in molecular biology · 2026
    Article
  3. Plasma Cystine as a Marker of Acute Stroke Severity.Diagnostics (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Role of hydrogen sulfide in subarachnoid hemorrhage.CNS neuroscience & therapeutics · 2022
    Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Tong LiDepartment of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, China.
Lingxiao WangDepartment of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, China.
Quan HuDepartment of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, China.
Song LiuDepartment of Physiology, Shandong University School of Medicine, Jinan, China.
Xuemei BaiDepartment of Physiology, Shandong University School of Medicine, Jinan, China.
Yunkai XieDepartment of Physiology, Shandong University School of Medicine, Jinan, China.
Tiantian ZhangDepartment of Physiology, Shandong University School of Medicine, Jinan, China.
Shishi BoDepartment of Physiology, Shandong University School of Medicine, Jinan, China.
Xiangqian GaoDepartment of Pathology, Binzhou Medical University Hospital, Binzhou, China.
Shuhua WuDepartment of Pathology, Binzhou Medical University Hospital, Binzhou, China.
Gang LiDepartment of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, China.
Zhen WangDepartment of Physiology, Shandong University School of Medicine, Jinan, China.
Shandong University · CNQilu Hospital of Shandong University · CNBinzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

l-Cysteine is a semi-essential amino acid and substrate for cystathionine-β-synthase (CBS) in the central nervous system. We previously reported that NaHS, an H

Indexed as

cystathionine-β-synthaseearly brain injuryH2Sl-cysteinesubarachnoid hemorrhage

Identifiers

PMID28512446
PMCPMC5411453
OpenAlexW2611068087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.