Evidence map›Paper›PMID 28512185›Full record

ArticleGenetics2017

Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the

Amanda R Brock, Mabel Seto, Rachel K Smith-Bolton

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 46 citations in OpenAlex.

  1. Draper-mediated efferocytosis bybioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Article
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  6. Article
  7. Article
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  10. Article
  11. Protein modification regulated autophagy inFrontiers in physiology · 2023
    Review
  12. Imaginal Disc Regeneration: Something Old, Something New.Cold Spring Harbor perspectives in biology · 2022
    Review
  13. The wing imaginal disc.Genetics · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. JNK Signaling inInternational journal of molecular sciences · 2021
    Review
  18. Article
  19. Article
  20. Model systems for regeneration:Development (Cambridge, England) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amanda R BrockDepartment of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801.
Mabel SetoDepartment of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801.
Rachel K Smith-BoltonDepartment of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 rsbolton@illinois.edu.
University of Illinois Urbana-Champaign · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Regulation of Cell Fate and Patterning During Regenerative GrowthR01GM107140 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SMITH-BOLTON, RACHEL · 2016 to 2020
$1.7M
NIGMS NIH HHS R01 GM107140NIH HHS P40 OD018537
6 · The paper itself

Abstract

Regeneration is a complex process that requires an organism to recognize and repair tissue damage, as well as grow and pattern new tissue. Here, we describe a genetic screen to identify novel regulators of regeneration. We ablated the

Indexed as

RegenerationAnimalsDrosophila melanogasterDrosophila ProteinsImaginal DiscsMAP Kinase Kinase 4MAP Kinase Signaling SystemReactive Oxygen SpeciesRepressor ProteinsWings, Animalcnc protein, DrosophilaDrosophila ProteinsMAP Kinase Kinase 4Reactive Oxygen SpeciesRepressor ProteinsCap-n-collarDrosophilaimaginal discNrf2reactive oxygen speciesregeneration

Identifiers

PMID28512185
PMCPMC5500147
OpenAlexW2614658890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.