Evidence map›Paper›PMID 28512145›Full record

ArticleScience signaling2017

The cytotoxic type 3 secretion system 1 of

Nicole J De Nisco, Mohammed Kanchwala, Peng Li, Jessie Fernandez, Chao Xing, Kim Orth

Abstract read
In one paragraph

Article in Science signaling, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Animals : an open access journal from MDPI · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Prophage-Related GeneFrontiers in cellular and infection microbiology · 2020
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Nicole J De NiscoDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID http://orcid.org/0000-0002-7670-5301
Mohammed KanchwalaMcDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID http://orcid.org/0000-0001-6035-2970
Peng LiDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Jessie FernandezDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID http://orcid.org/0000-0002-0897-2707
Chao XingMcDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID http://orcid.org/0000-0002-1838-0502
Kim OrthDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. kim.orth@utsouthwestern.edu.ORCID http://orcid.org/0000-0002-0678-7620
The University of Texas Southwestern Medical Center · USSouthwestern Medical Center · USHoward Hughes Medical Institute · US

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
MOLECULAR MICROBIOLOGY TRAINING GRANTT32AI007520 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Julie K Pfeiffer · 1997 to 2026
$7.0M
Biochemical Characterization of Yersinia Effector YopJ.R01AI056404 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI ORTH, KIM · 2003 to 2012
$2.8M
Infectious Diseases Training ProgramT32AI070116 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI PERL, TRISH M. · 2007 to 2017
$1.1M
NCATS NIH HHS UL1 TR001105NIAID NIH HHS R01 AI056404NIAID NIH HHS T32 AI007520NIAID NIH HHS T32 AI070116
6 · The paper itself

Abstract

Bacterial effectors potently manipulate host signaling pathways. The marine bacterium

Indexed as

Gene ExpressionAnimalsAutophagyBacterial ProteinsBacterial ToxinsCell SurvivalGene Expression ProfilingGenome-Wide Association StudyHeLa CellsHost-Pathogen InteractionsHumansMicePrimary Cell CultureRAW 264.7 Cellsrho GTP-Binding ProteinsRNABacterial ProteinsBacterial Toxinsrho GTP-Binding ProteinsRNAType III Secretion Systems

Identifiers

PMID28512145
PMCPMC5662193
OpenAlexW2614213024

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.