Evidence map›Paper›PMID 28512097›Full record

ArticlemBio2017

Glutathionylation of

Anthony Mitchell, Christina Tam, Derek Elli, Thomas Charlton, Patrick Osei-Owusu, Farbod Fazlollahi, Kym F Faull, Olaf Schneewind

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Discovery ofActa pharmaceutica Sinica. B · 2025
    Article
  3. Review
  4. Article
  5. Host Epigenetics in Intracellular Pathogen Infections.International journal of molecular sciences · 2020
    Review
  6. Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria.Frontiers in cellular and infection microbiology · 2020
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anthony MitchellHoward T. Ricketts Laboratory, Argonne National Laboratory, Lemont, lllinois, USA.
Christina TamHoward T. Ricketts Laboratory, Argonne National Laboratory, Lemont, lllinois, USA.
Derek ElliHoward T. Ricketts Laboratory, Argonne National Laboratory, Lemont, lllinois, USA.
Thomas CharltonHoward T. Ricketts Laboratory, Argonne National Laboratory, Lemont, lllinois, USA.
Patrick Osei-OwusuHoward T. Ricketts Laboratory, Argonne National Laboratory, Lemont, lllinois, USA.
Farbod FazlollahiMass Spectrometry Laboratory, Department of Psychiatry and Biobehavioral Sciences, Semel Institute of Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Kym F FaullMass Spectrometry Laboratory, Department of Psychiatry and Biobehavioral Sciences, Semel Institute of Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Olaf SchneewindHoward T. Ricketts Laboratory, Argonne National Laboratory, Lemont, lllinois, USA oschnee@bsd.uchicago.edu.
Argonne National Laboratory · USUniversity of California, Los Angeles · USUniversity of Chicago · US

Funding

Vaccines and Therapies Against BotulismU54AI057153 · NIAID · UNIVERSITY OF CHICAGO · PI BUBECK WARDENBURG, JULIANE · 2003 to 2013
$87.6M
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)T32HD007009 · NICHD · UNIVERSITY OF CHICAGO · PI NANCY B SCHWARTZ · 1985 to 2026
$13.0M
Technology CoreU19AI107792 · NIAID · UNIVERSITY OF CHICAGO · PI BABNIGG, GYORGY · 2013 to 2017
$4.3M
Yersinia Type III Transport of Yop Proteins into Immune CellsR01AI042797 · NIAID · UNIVERSITY OF CHICAGO · PI SCHNEEWIND, OLAF · 1998 to 2013
$4.3M
Thermo Vantage triple quadrupole with FAIMS and Accela UPLCS10RR023718 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FAULL, KYM FRANCIS · 2010 to 2010
$494k
Safe and universal live-attenuated plague vaccineR21AI119725 · NIAID · UNIVERSITY OF CHICAGO · PI SCHNEEWIND, OLAF · 2015 to 2016
$435k
NCRR NIH HHS S10 RR023718NIAID NIH HHS R01 AI042797NIAID NIH HHS R21 AI119725NIAID NIH HHS U19 AI107792NIAID NIH HHS U54 AI057153NICHD NIH HHS T32 HD007009
6 · The paper itself

Abstract

Glutathionylation, the formation of reversible mixed disulfides between glutathione and protein cysteine residues, is a posttranslational modification previously observed for intracellular proteins of bacteria. Here we show that

Indexed as

AnimalsAntigens, BacterialApoptosisCell LineCysteineCytokinesDisease Models, AnimalDisulfidesFemaleGlutathioneGlutathione SynthaseHost-Pathogen InteractionsHumansImmunity, InnateMacrophagesMass SpectrometryAntigens, BacterialCysteineCytokinesDisulfidesGlutathioneGlutathione SynthaseLcrV protein, YersiniaPore Forming Cytotoxic Proteinsglutathionylationinnate immunitymacrophageplagueribosomal protein S3 (RPS3)Yersinia pestis

Identifiers

PMID28512097
PMCPMC5433101
OpenAlexW2616233563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.