Evidence map›Paper›PMID 28511921›Full record

ReviewCellular immunology2017

Myeloperoxidase: A new player in autoimmunity.

Anna Strzepa, Kirkwood A Pritchard, Bonnie N Dittel

Open access · greenAbstract readReview
In one paragraph

Review in Cellular immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 2 syntheses or guidelines pooled it, 226 citations in OpenAlex.

  1. Pooled it
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  7. Substrate for Thyroid Hormone Synthesis: Biochemistry, Evolution, and Physiology.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
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44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Anna StrzepaBlood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, United States; Department of Medical Biology, Faculty of Health Sciences, Jagiellonian University Medical College, ul. Kopernika 7, 31-034 Krakow, Poland.
Kirkwood A PritchardDepartment of Surgery, Division of Pediatric Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.
Bonnie N DittelBlood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, United States; Department of Microbiology and Immunology, School of Pharmacy, Medical College of Wisconsin, Milwaukee, WI, United States. Electronic address: bonnie.dittel@bcw.edu.
Medical College of Wisconsin · USJagiellonian University · PL

Funding

Mechanisms of Inflammation in Sickle Cell DiseaseR01HL128371 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI PRITCHARD, KIRKWOOD ARTHUR · 2016 to 2024
$4.2M
Biophysics of HDL DysfunctionR01HL112270 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI PRITCHARD, KIRKWOOD ARTHUR, SORCI-THOMAS, MARY G · 2012 to 2015
$2.5M
Asthma Increases Vaso-occlusion in Sickle Cell DiseaseR01HL102836 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HILLERY, CHERYL A, PRITCHARD, KIRKWOOD ARTHUR · 2010 to 2013
$2.2M
The Role of B Cells in Regulating AutoimmunityR01AI069358 · NIAID · VERSITI WISCONSIN, INC. · PI DITTEL, BONNIE N · 2008 to 2012
$2.0M
Mechanisms of a novel regulatory B cell subsetR56AI122655 · NIAID · VERSITI WISCONSIN, INC. · PI DITTEL, BONNIE N · 2016 to 2016
$418k
NHLBI NIH HHS R01 HL102836NHLBI NIH HHS R01 HL112270NHLBI NIH HHS R01 HL128371NIAID NIH HHS R01 AI069358NIAID NIH HHS R56 AI122655
6 · The paper itself

Abstract

Myeloperoxidase (MPO) is the most toxic enzyme found in the azurophilic granules of neutrophils. MPO utilizes H

Indexed as

AutoimmunityAnimalsAutoimmune DiseasesCapillary PermeabilityDendritic CellsHumansInflammationMiceMolecular Targeted TherapyPeroxidasePeroxidaseAutoimmunityMultiple sclerosisMyeloperoxidaseNeutrophilOxidative stressRheumatoid arthritis

Identifiers

PMID28511921
PMCPMC5665680
OpenAlexW2612474028

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.