Evidence map›Paper›PMID 28511717›Full record

ReviewGenome medicine2017

Pancreatic β-cell regeneration: advances in understanding the genes and signaling pathways involved.

Solomon Afelik, Meritxell Rovira

Erratum issuedAbstract readEditorialReview
In one paragraph

Review in Genome medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Solomon AfelikDivision of Transplantation, Department of Surgery, University of Illinois at Chicago, 840 South Wood Street, CSB 920 (Rm 502), Chicago, IL, 60612, USA. safelik@uic.edu.
Meritxell RoviraCenter of Regenerative Medicine in Barcelona (CMRB), Dr. Aiguader 88, 08003, Barcelona, Spain. mrovira@cmrb.eu.ORCID 0000-0002-0538-4846

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in β-cell regeneration in vivo are providing insights into the mechanisms involved in the conversion of distinct pancreatic cell lineages into β cells. These mechanisms mostly involve reactivation of the gene encoding the pancreatic endocrine cell-specifying transcription factor neurogenin-3.

Indexed as

Basic Helix-Loop-Helix ProteinsNerve Tissue ProteinsRegenerationSignal TransductionHumansInsulin-Secreting CellsBasic Helix-Loop-Helix ProteinsNerve Tissue ProteinsNEUROG3 protein, human

Identifiers

PMID28511717
PMCPMC5434582

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.