ArticleJournal of clinical and diagnostic research : JCDR2017
Study on Steroid Induced Ocular Findings in Children with Nephrotic Syndrome.
Article in Journal of clinical and diagnostic research : JCDR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- Risk factors and critical thresholds for glucocorticoid-induced ocular adverse reactions in children: implications for muscle and neuromuscular disease management.European journal of translational myology · 2026Article
- Purtscher-like retinopathy presenting as acute vision loss in childhood nephrotic syndrome: case report with review of literature.CEN case reports · 2026Review
- Prevalence of corticosteroid-induced cataracts in children with nephrotic syndrome: a cross-sectional study in Pakistan.Childhood kidney diseases · 2026Article
- Outcomes Using a Standardized Provincial Childhood Nephrotic Syndrome Clinical Pathway.Canadian journal of kidney health and disease · 2024Article
- Evaluation of Visual Acuity, Macular Thickness, and Level of Proteinuria in Children with Nephrotic Syndrome.Korean journal of ophthalmology : KJO · 2023Article
- Prevalence and predictors of ocular complications among children undergoing nephrotic syndrome treatment in a resource-limited setting.BMC ophthalmology · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLong term use of corticosteroids in Nephrotic Syndrome (NS) is associated with ocular complications such as Posterior Subcapsular Cataract (PSC), glaucoma, increased intra-ocular pressure, ptosis, mydriasis, eyelid skin atrophy, keratisis, thinning of cornea and sclera, repeated hordeolum exacerbations.
aimTo determine ocular abnormalities in children with NS and their association with steroid dosing and duration. MATERIALS AND
methodsHundred patients with NS in the age group of 2-18 years, with no evidence of other systemic disease, were considered for the study. Group I included cases (66) who took standard steroid regimen for first episode of NS. Group II included cases (34) who took steroid irrationally (daily basis for long time) other than standard regimen. Steroid induced ocular complications were compared in both groups after detailed ophthalmological examination. Statistical analysis was done using Statistical Package for Social Science (SPSS-20.0).
resultsOcular abnormalities were found in 12 patients out of 66 in Group I (18%) and 16 patients out of 34 patients in Group II (47%). Out of 12 patients of Group I who had ocular problems, three had myopic astigmatism, eight patients had PSC and one had temporal disc pallor. While in Group II, out of 16 patients who had ocular complications, two patients had raised intra ocular pressure and two patients had myopic astigmatism and 12 patients had posterior sub capsular cataract. The difference in mean cumulative steroid doses in both groups was statistically significant but no such difference was there between duration of steroid intake in both group.
conclusionOur study concluded that ocular complications were more common in patients with irrationally steroid intake and cumulative steroid dose intake was also significantly higher in same patients.
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