ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2017
Liver Stiffness Assessed by Shear Wave Elastography Predicts Postoperative Liver Failure in Patients with Hepatocellular Carcinoma.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Diagnostic Performance of SWE and Predictive Models Based on SWE for Post- Hepatectomy Liver Failure: A Systematic Review and Meta-analysis.Current medical imaging · 2025Pooled it
- Assessment of the postoperative prognosis in patients with hepatocellular carcinoma using vibration-controlled transient elastography: A systemic review and meta-analysis.Clinical and molecular hepatology · 2024Pooled it
- Pooled it
- China Liver Cancer Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (2024 Edition).Liver cancer · 2025Article
- Nomogram based on liver stiffness and spleen area with ultrasound for posthepatectomy liver failure: A multicenter study.World journal of gastroenterology · 2024Observational
- Relationship between portal hypertension and liver stiffness measurements in the treatment of hepatocellular carcinoma from the surgeon's point of view in the Baveno VII era.Hepatobiliary surgery and nutrition · 2024Article
- Article
- Predicting symptomatic post-hepatectomy liver failure in patients with hepatocellular carcinoma: development and validation of a preoperative nomogram.European radiology · 2023Article
- Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2022 Edition).Liver cancer · 2023Article
- E-AHPBA-ESSO-ESSR Innsbruck consensus guidelines for preoperative liver function assessment before hepatectomy.The British journal of surgery · 2023Article
- Nomogram based on CT-derived extracellular volume for the prediction of post-hepatectomy liver failure in patients with resectable hepatocellular carcinoma.European radiology · 2022Article
- Clinical value of predictive models based on liver stiffness measurement in predicting liver reserve function of compensated chronic liver disease.World journal of gastroenterology · 2022Article
- Liver stiffness assessed by real-time two-dimensional shear wave elastography predicts hypersplenism in patients with Wilson's disease: a prospective study.BMC medical imaging · 2022Article
- Liver Stiffness Measured by Two-Dimensional Shear Wave Elastography for Predicting Symptomatic Post-hepatectomy Liver Failure in Patients with Hepatocellular Carcinoma.Annals of surgical oncology · 2022Article
- Development and Validation of a Nomogram Based on Perioperative Factors to Predict Post-hepatectomy Liver Failure.Journal of clinical and translational hepatology · 2021Article
- Simulation of portal/hepatic vein associated remnant liver ischemia/congestion by three-dimensional visualization technology based on preoperative CT scan.Annals of translational medicine · 2021Article
- Comparison between preoperative two-dimensional shear wave elastography and indocyanine green clearance test for prediction of post-hepatectomy liver failure.Quantitative imaging in medicine and surgery · 2021Article
- Comparison of preoperative two-dimensional shear wave elastography, indocyanine green clearance test and biomarkers for post hepatectomy liver failure prediction in patients with hepatocellular carcinoma.BMC gastroenterology · 2021Article
- Development and validation of a nomogram combining hematological and imaging features for preoperative prediction of microvascular invasion in hepatocellular carcinoma patients.Annals of translational medicine · 2021Article
- Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (2019 Edition).Liver cancer · 2020Article
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundCirrhosis increases a patient's risk of developing postoperative liver failure (PLF). Liver stiffness (LS), assessed by two-dimensional shear wave elastography (SWE), indicates liver fibrosis with high accuracy. Whether LS is superior to portal hypertension (PHT) in predicting PLF remains to be studied.
methodsThe study enrolled 280 patients who underwent hepatectomy for hepatocellular carcinoma from July 2015 to July 2016. All patients received preoperative assessments for LS, PHT, and serum markers of liver fibrosis in addition to other clinicopathological tests. Risk factors for grade A and grade B (or greater) PLF were subjected to univariate and multivariate analysis and receiver operating characteristic curve analysis.
resultsFifty-five patients (19.6%) experienced PLF. The cutoff value of LS for predicting cirrhosis was 10.1 kPa. Multivariate analysis identified LS, hyaluronic acid, IV collagen, and the presence of splenomegaly as independent predictors of PLF. The cutoff value of LS for predicting PLF and grade B (or greater) PLF was 11.75 and 11.9 kPa, respectively. LS was superior to PHT in predicting PLF or greater than grade B PLF (0.72 vs. 0.60, 0.76 vs. 0.59, P < 0.05).
conclusionLS measured by SWE can predict risk of PLF with greater accuracy than PHT.
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