Evidence map›Paper›PMID 28510420›Full record

ArticleEnvironmental science & technology2017

Nontarget Analysis Reveals a Bacterial Metabolite of Pyrene Implicated in the Genotoxicity of Contaminated Soil after Bioremediation.

Zhenyu Tian, Avram Gold, Jun Nakamura, Zhenfa Zhang, Joaquim Vila, David R Singleton, Leonard B Collins, Michael D Aitken

Open access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhenyu TianDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , CB 7431, Chapel Hill, North Carolina 27599-7431, United States.ORCID http://orcid.org/0000-0002-7491-7028
Avram GoldDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , CB 7431, Chapel Hill, North Carolina 27599-7431, United States.
Jun NakamuraDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , CB 7431, Chapel Hill, North Carolina 27599-7431, United States.
Zhenfa ZhangDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , CB 7431, Chapel Hill, North Carolina 27599-7431, United States.
Joaquim VilaDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , CB 7431, Chapel Hill, North Carolina 27599-7431, United States.
David R SingletonDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , CB 7431, Chapel Hill, North Carolina 27599-7431, United States.
Leonard B CollinsDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , CB 7431, Chapel Hill, North Carolina 27599-7431, United States.
Michael D AitkenDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , CB 7431, Chapel Hill, North Carolina 27599-7431, United States.
University of North Carolina at Chapel Hill · US

Funding

STOCHASTIC ANALYSIS OF FLOW AND TRANSPORT PHENOMENAP42ES005948 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRY, REBECCA · 1992 to 2017
$45.4M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
NIEHS NIH HHS P30 ES010126NIEHS NIH HHS P42 ES005948
6 · The paper itself

Abstract

Bioremediation is an accepted technology for cleanup of soil contaminated with polycyclic aromatic hydrocarbons (PAHs), but it can increase the genotoxicity of the soil despite removal of the regulated PAHs. Although polar biotransformation products have been implicated as causative genotoxic agents, no specific product has been identified. We pursued a nontarget analytical approach combining effect-directed analysis (EDA) and metabolite profiling to compare extracts of PAH-contaminated soil from a former manufactured-gas plant site before and after treatment in a laboratory-scale aerobic bioreactor. A compound with the composition C

Indexed as

Biodegradation, EnvironmentalPyrenesSoil PollutantsPolycyclic Aromatic HydrocarbonsSoilSoil MicrobiologyPolycyclic Aromatic HydrocarbonsPyrenesSoilSoil Pollutants

Identifiers

PMID28510420
PMCPMC6309544
OpenAlexW2614218019

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.