Evidence map›Paper›PMID 28510069›Full record

ReviewBiophysical reviews2010

Multi-dimensional correlative imaging of subcellular events: combining the strengths of light and electron microscopy.

Yingying Su, Marko Nykanen, Kristina A Jahn, Renee Whan, Laurence Cantrill, Lilian L Soon, Kyle R Ratinac, Filip Braet

Abstract readReview
In one paragraph

Review in Biophysical reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. In focus in HCB.Histochemistry and cell biology · 2018
    Article
  11. Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingying SuAustralian Centre for Microscopy and Microanalysis, The University of Sydney, Madsen Building F09, Sydney, NSW, 2006, Australia.
Marko NykanenKids Research Institute, Children's Hospital Westmead, Westmead, Locked Bag 4001, NSW, 2145, Australia.
Kristina A JahnAustralian Centre for Microscopy and Microanalysis, The University of Sydney, Madsen Building F09, Sydney, NSW, 2006, Australia.
Renee WhanAustralian Centre for Microscopy and Microanalysis, The University of Sydney, Madsen Building F09, Sydney, NSW, 2006, Australia.
Laurence CantrillKids Research Institute, Children's Hospital Westmead, Westmead, Locked Bag 4001, NSW, 2145, Australia.
Lilian L SoonAustralian Centre for Microscopy and Microanalysis, The University of Sydney, Madsen Building F09, Sydney, NSW, 2006, Australia.
Kyle R RatinacAustralian Centre for Microscopy and Microanalysis, The University of Sydney, Madsen Building F09, Sydney, NSW, 2006, Australia.
Filip BraetAustralian Centre for Microscopy and Microanalysis, The University of Sydney, Madsen Building F09, Sydney, NSW, 2006, Australia. filip.braet@sydney.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To genuinely understand how complex biological structures function, we must integrate knowledge of their dynamic behavior and of their molecular machinery. The combined use of light or laser microscopy and electron microscopy has become increasingly important to our understanding of the structure and function of cells and tissues at the molecular level. Such a combination of two or more different microscopy techniques, preferably with different spatial- and temporal-resolution limits, is often referred to as 'correlative microscopy'. Correlative imaging allows researchers to gain additional novel structure-function information, and such information provides a greater degree of confidence about the structures of interest because observations from one method can be compared to those from the other method(s). This is the strength of correlative (or 'combined') microscopy, especially when it is combined with combinatorial or non-combinatorial labeling approaches. In this topical review, we provide a brief historical perspective of correlative microscopy and an in-depth overview of correlative sample-preparation and imaging methods presently available, including future perspectives on the trend towards integrative microscopy and microanalysis.

Indexed as

Combinatorial labelingCombined microscopyCorrelative morphomicsElectron tomographyIntegrated microscopyLive-cell imaging

Identifiers

PMID28510069
PMCPMC5418370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.