Evidence map›Paper›PMID 28510000›Full record

ReviewBiophysical reviews2012

Actin in striated muscle: recent insights into assembly and maintenance.

Joseph Dwyer, Thomas Iskratsch, Elisabeth Ehler

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biophysical reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. AnJournal of the Royal Society, Interface · 2024
    Article
  5. Review
  6. Review
  7. Two distinct phosphorylation events govern the function of muscle FHOD3.Cellular and molecular life sciences : CMLS · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joseph DwyerThe Randall Division of Cell and Molecular Biophysics and The Cardiovascular Division, King's College London, British Heart Foundation Centre of Research Excellence, New Hunt's House, Guy's Campus, London, SE1 1UL, UK.
Thomas IskratschThe Randall Division of Cell and Molecular Biophysics and The Cardiovascular Division, King's College London, British Heart Foundation Centre of Research Excellence, New Hunt's House, Guy's Campus, London, SE1 1UL, UK.
Elisabeth EhlerThe Randall Division of Cell and Molecular Biophysics and The Cardiovascular Division, King's College London, British Heart Foundation Centre of Research Excellence, New Hunt's House, Guy's Campus, London, SE1 1UL, UK. Elisabeth.ehler@kcl.ac.uk.

Funding

Medical Research Council G0400153
6 · The paper itself

Abstract

Striated muscle cells are characterised by a para-crystalline arrangement of their contractile proteins actin and myosin in sarcomeres, the basic unit of the myofibrils. A multitude of proteins is required to build and maintain the structure of this regular arrangement as well as to ensure regulation of contraction and to respond to alterations in demand. This review focuses on the actin filaments (also called thin filaments) of the sarcomere and will discuss how they are assembled during myofibrillogenesis and in hypertrophy and how their integrity is maintained in the working myocardium.

Indexed as

ActinCardiomyopathyForminMyofibrillogenesisSarcomere

Identifiers

PMID28510000
PMCPMC5425700

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.