Evidence map›Paper›PMID 28509999›Full record

ReviewBiophysical reviews2012

Voltage sensor of ion channels and enzymes.

Carlos Gonzalez, Gustavo F Contreras, Alexander Peyser, Peter Larsson, Alan Neely, Ramón Latorre

Open access · bronzeAbstract readReview
In one paragraph

Review in Biophysical reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Atomistic Insights of Calmodulin Gating of Complete Ion Channels.International journal of molecular sciences · 2020
    Review
  8. Article
  9. Charge of the Proton Channel.Biophysical journal · 2018
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Carlos GonzalezCentro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Pasaje Harrington 287, Valparaíso, 2360103, Chile.
Gustavo F ContrerasCentro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Pasaje Harrington 287, Valparaíso, 2360103, Chile.
Alexander PeyserDepartment of Physiology and Biophysics, University of Miami, Miami, FL, USA.
Peter LarssonDepartment of Physiology and Biophysics, University of Miami, Miami, FL, USA.
Alan NeelyCentro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Pasaje Harrington 287, Valparaíso, 2360103, Chile.
Ramón LatorreCentro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Pasaje Harrington 287, Valparaíso, 2360103, Chile. ramon.latorre@uv.cl.
Valparaiso University · USUniversity of Miami · USUniversity of Valparaíso · CL

Funding

Molecular mechanisms of voltage-gated proton channelsR01HL095920 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LARSSON, HANS PETER · 2010 to 2013
$1.5M
NHLBI NIH HHS R01 HL095920
6 · The paper itself

Abstract

Placed in the cell membrane (a two-dimensional environment), ion channels and enzymes are able to sense voltage. How these proteins are able to detect the difference in the voltage across membranes has attracted much attention, and at times, heated debate during the last few years. Sodium, Ca

Indexed as

BK channelsCav ChannelsKv channelsProton channels and VSPVoltage sensor

Identifiers

PMID28509999
PMCPMC5425699
OpenAlexW1991248935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.