Evidence map›Paper›PMID 28508638›Full record

ArticleOrganic letters2017

Determination of the Absolute Configuration of β-Chiral Primary Alcohols Using the Competing Enantioselective Conversion Method.

Alexander S Burns, Alexander J Wagner, Jennifer L Fulton, Kyle Young, Armen Zakarian, Scott D Rychnovsky

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Isothiourea-Catalyzed Acylative Kinetic Resolution of Tertiary α-Hydroxy Esters.Angewandte Chemie (International ed. in English) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander S BurnsDepartment of Chemistry, University of California at Irvine , 1102 Natural Sciences II, Irvine, California 92697, United States.
Alexander J WagnerDepartment of Chemistry, University of California at Irvine , 1102 Natural Sciences II, Irvine, California 92697, United States.
Jennifer L FultonDepartment of Chemistry, University of California at Irvine , 1102 Natural Sciences II, Irvine, California 92697, United States.
Kyle YoungDepartment of Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Armen ZakarianDepartment of Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.ORCID 0000-0002-9120-1232
Scott D RychnovskyDepartment of Chemistry, University of California at Irvine , 1102 Natural Sciences II, Irvine, California 92697, United States.ORCID 0000-0002-7223-4389

Funding

Total synthesis of bioactive natural productsR01GM077379 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI SERVENT, DENIS, ZAKARIAN, ARMEN · 2008 to 2021
$5.3M
NIGMS NIH HHS R01 GM077379
6 · The paper itself

Abstract

A method for determining the absolute configuration of β-chiral primary alcohols has been developed. Enantioenriched alcohols were acylated in the presence of either enantiomer of the enantioselective acylation catalyst HBTM, and the faster reaction was determined by measuring product conversion using

Indexed as

AcylationAlcoholsCatalysisMolecular StructureStereoisomerismAlcohols

Identifiers

PMID28508638
PMCPMC6364845

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.