Evidence map›Paper›PMID 28508552›Full record

ArticleAngewandte Chemie (International ed. in English)2017

Real-Time Analysis of Folding upon Binding of a Disordered Protein by Using Dissolution DNP NMR Spectroscopy.

Mukundan Ragavan, Luigi I Iconaru, Cheon-Gil Park, Richard W Kriwacki, Christian Hilty

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
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  6. Review
  7. Inversion of HyperpolarizedThe journal of physical chemistry. B · 2022
    Article
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  16. [Scientific reports · 2019
    Article
  17. Review
  18. Laser- and cryogenic probe-assisted NMR enables hypersensitive analysis of biomolecules at submicromolar concentration.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  19. Additive fabrication for NMR probe builders.Progress in nuclear magnetic resonance spectroscopy
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Mukundan RagavanDepartment of Biochemistry & Biophysics, Texas A&M University, College Station, TX, 77843, USA.
Luigi I IconaruDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Cheon-Gil ParkDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Richard W KriwackiDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Christian HiltyDepartment of Chemistry, Texas A&M University, College Station, TX, 77843, USA.
St. Jude Children's Research Hospital · USFlorida College · USTexas A&M University · USUniversity of Tennessee Health Science Center · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Structural Determinants in Cell Growth Control by p21 and p27R01CA082491 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KRIWACKI, RICHARD W · 2001 to 2011
$2.7M
NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA082491
6 · The paper itself

Abstract

The kinase inhibitory domain of the cell cycle regulatory protein p27

Indexed as

Protein FoldingCyclin ACyclin-Dependent Kinase 2Cyclin-Dependent Kinase Inhibitor p27Intrinsically Disordered ProteinsMagnetic Resonance SpectroscopyProtein BindingProtein Structure, SecondarySolubilityTime FactorsCyclin ACyclin-Dependent Kinase 2Cyclin-Dependent Kinase Inhibitor p27Intrinsically Disordered Proteinshyperpolarizationintrinsically disordered proteinsNMR spectroscopyprotein foldingprotein-protein interactions

Identifiers

PMID28508552
PMCPMC5674774
OpenAlexW2614529749

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.