Evidence map›Paper›PMID 28508315›Full record

ReviewAdvances in experimental medicine and biology2017

TRPC Channels and Parkinson's Disease.

Pramod Sukumaran, Yuyang Sun, Anne Schaar, Senthil Selvaraj, Brij B Singh

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Sigma1 Receptor Inhibits TRPC1-Mediated CaCellular and molecular neurobiology · 2021
    Article
  6. Review
  7. Calmodulin and Its Binding Proteins in Parkinson's Disease.International journal of molecular sciences · 2021
    Review
  8. Review
  9. Review
  10. Memory and Learning Deficits Are Associated With CaFrontiers in aging neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pramod SukumaranDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, 58201, USA.
Yuyang SunDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, 58201, USA.
Anne SchaarDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, 58201, USA.
Senthil SelvarajDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, 58201, USA.
Brij B SinghDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, 58201, USA. brij.singh@med.und.edu.
University of North Dakota · US

Funding

Yersina perstis interactions with macrophagesP20GM113123 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI COMBS, COLIN K · 2016 to 2025
$19.9M
TRPC1, Calcium, and Saliva SecretionR01DE017102 · NIDCR · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Brij B Singh · 2006 to 2026
$7.5M
Epigenetic regulations in Sjogern's syndromeR01DE022765 · NIDCR · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SINGH, BRIJ B · 2017 to 2021
$1.8M
Galectins as novel alarmins in salivary gland inflammationR21DE024300 · NIDCR · UNIVERSITY OF NORTH DAKOTA · PI MISHRA, BIBHUTI BHUSAN, SINGH, BRIJ B · 2015 to 2016
$382k
NIDCR NIH HHS R01 DE017102NIDCR NIH HHS R01 DE022765NIDCR NIH HHS R21 DE024300NIGMS NIH HHS P20 GM113123NIH HHS DE017102NIH HHS DE024300NIH HHS GM113123
6 · The paper itself

Abstract

Parkinson's disease (PD) is a common neurodegenerative disorder, which involves degeneration of dopaminergic neurons that are present in the substantia nigra pars compacta (SNpc) region. Many factors have been identified that could lead to Parkinson's disease; however, almost all of them are directly or indirectly dependent on Ca

Indexed as

AnimalsBrainCalciumDopaminergic NeuronsHumansParkinson DiseaseTRPC Cation ChannelsCalciumTRPC Cation ChannelsCalcium signalingDopaminergic neuronsER stressOxidative stressParkinson’s disease

Identifiers

PMID28508315
PMCPMC5937936
OpenAlexW2615308239

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.