Evidence map›Paper›PMID 28508204›Full record

ArticleDoklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections2017

Rearing by foster Wistar mother with high level of maternal care counteracts the development of genetic absence epilepsy and comorbid depression in WAG/Rij rats.

K Yu Sarkisova, A V Gabova, M A Kulikov, E A Fedosova, A B Shatskova, A A Morosov

Abstract read
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In one paragraph

Article in Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Gender-Dependent Effect of Maternal Methyl-Enriched Diet on the Expression of Genetic Absence Epilepsy and Comorbid Depression in Adult Offspring of WAG/Rij Rats.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

K Yu SarkisovaInstitute of Higher Nervous Activity and Neurophysiology RAS, Moscow, Russia. karine.online@yandex.ru.
A V GabovaInstitute of Higher Nervous Activity and Neurophysiology RAS, Moscow, Russia.
M A KulikovInstitute of Higher Nervous Activity and Neurophysiology RAS, Moscow, Russia.
E A FedosovaInstitute of Higher Nervous Activity and Neurophysiology RAS, Moscow, Russia.
A B ShatskovaInstitute of Higher Nervous Activity and Neurophysiology RAS, Moscow, Russia.
A A MorosovInstitute of Radio Engineering and Radioelectronics RAS, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been shown for the first time that rearing by a foster Wistar mother with high level of maternal care (MC) counteracts the expression of genetic absence epilepsy (AE) and comorbid depression - reduces the number, duration and index of spike-wave discharges (SWDs) and immobility time in the forced swimming test, as well as exerts substantial effects on morphology and time-frequency dynamics of SWDs in WAG/Rij rats. It is supposed that increases in MC early in development might be used to counteract epileptogenesis and comorbid depression in people genetically predisposed to AE.

Indexed as

AnimalsBehavior, AnimalDepressionDisease Models, AnimalElectroencephalographyEpilepsy, AbsenceFemaleHumansMaleMaternal BehaviorMothersRats

Identifiers

PMID28508204

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.