Evidence map›Paper›PMID 28508165›Full record

ArticleParasitology research2017

Frequency of Toxoplasma gondii in the retina in eye banks in Brazil.

Deise F Costa, Heloisa Nascimento, Aline Sutili, Fernando A J Nobrega, Flavio Fowler, Mario Junqueira Nobrega, Cristina Garrido, Janaina de Oliveira Dias, Consuelo B D Adán, Luiz Vicente Rizzo and 3 more

Abstract read
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In one paragraph

Article in Parasitology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Deise F CostaDepartment of Ophthalmology, Federal University of Sao Paulo and Vision Institute, Rua Botucatu, 821, São Paulo, SP, 04023-062, Brazil.
Heloisa NascimentoDepartment of Ophthalmology, Federal University of Sao Paulo and Vision Institute, Rua Botucatu, 821, São Paulo, SP, 04023-062, Brazil.
Aline SutiliDepartment of Ophthalmology, Federal University of Sao Paulo and Vision Institute, Rua Botucatu, 821, São Paulo, SP, 04023-062, Brazil.
Fernando A J NobregaEye Bank of Joinville, Joinville, SC, Brazil.
Flavio FowlerDepartment of Ophthalmology, Federal University of Sao Paulo and Vision Institute, Rua Botucatu, 821, São Paulo, SP, 04023-062, Brazil.
Mario Junqueira NobregaEye Bank of Joinville, Joinville, SC, Brazil.
Cristina GarridoEye Bank of Manaus, Manaus, AM, Brazil.
Janaina de Oliveira DiasEye Bank of Chapeco, Chapeco, SC, Brazil.
Consuelo B D AdánEye Bank of Sao Paulo, Sao Paulo, SP, Brazil.
Luiz Vicente RizzoHospital Israelita Albert Einstein, Sao Paulo, Brazil.
Claudio SilveiraClinica Silveira, Erechim, Rio Grande do Sul, Brazil.
Rubens BelfortDepartment of Ophthalmology, Federal University of Sao Paulo and Vision Institute, Rua Botucatu, 821, São Paulo, SP, 04023-062, Brazil.
Alessandra G CommodaroDepartment of Ophthalmology, Federal University of Sao Paulo and Vision Institute, Rua Botucatu, 821, São Paulo, SP, 04023-062, Brazil. alecommodaro@gmail.com.
Universidade Federal de São Paulo · BRInstituto da Visão · BRBank of Brazil · BRCommunity University of Chapecó Region - Unochapecó · BRHospital Israelita Albert Einstein · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ocular toxoplasmosis is the main cause of posterior uveitis worldwide frequently leading to vision loss. In Brazil, the seroprevalence of Toxoplasma gondii infection ranges from 50 to 80% depending of the region studied. The frequency of toxoplasmic retinal scar may reach 18% of the adults in the South of Brazil. Our goal was to determine the frequency of T. gondii DNA in retinas from eye banks from different regions in Brazil. A total of 162 eyes were obtained from eye banks in Manaus (n = 60), Sao Paulo (n = 60), Chapeco (n = 26), and Joinville (n = 16). The retinas were macroscopically analyzed and collected for DNA extraction. Real-time PCR (qPCR) was performed using the T. gondii B1 marker. By qPCR, a higher frequency of T. gondii DNA in the retinas from the eye bank of Joinville (25%) was found when compared to Manaus (5%). The retinas from Sao Paulo and Chapeco were qPCR negative. Clinical examination determined the retina lesions to be compatible with toxoplasmosis in the following frequencies: Joinville (62.5%), Manaus (10%), Sao Paulo (6.7%), and Chapeco (15.4%).

Indexed as

Eye BanksAdultAnimalsBrazilChoroiditisDNA, ProtozoanHumansReal-Time Polymerase Chain ReactionRetinaSeroepidemiologic StudiesToxoplasmaToxoplasmosis, OcularDNA, ProtozoanBrazilEye bankReal-time PCRToxoplasma gondii

Identifiers

PMID28508165
OpenAlexW2616821203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.