Evidence map›Paper›PMID 28508054›Full record

ArticleScience advances2017

Flexible adaptation of male germ cells from female iPSCs of endangered

Arata Honda, Narantsog Choijookhuu, Haruna Izu, Yoshihiro Kawano, Mizuho Inokuchi, Kimiko Honsho, Ah-Reum Lee, Hiroki Nabekura, Hiroshi Ohta, Tomoyuki Tsukiyama and 6 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. The making of cells and organs in xenogeneic animal bioreactor.Signal transduction and targeted therapy · 2026
    Review
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  11. Turnover of mammal sex chromosomes in theProceedings of the National Academy of Sciences of the United States of America · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Arata HondaOrganization for Promotion of Tenure Track, University of Miyazaki, Miyazaki 889-1692, Japan.
Narantsog ChoijookhuuDepartment of Histochemistry and Cell Biology, Department of Anatomy, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan.ORCID 0000-0002-3398-4785
Haruna IzuOrganization for Promotion of Tenure Track, University of Miyazaki, Miyazaki 889-1692, Japan.
Yoshihiro KawanoOrganization for Promotion of Tenure Track, University of Miyazaki, Miyazaki 889-1692, Japan.
Mizuho InokuchiOrganization for Promotion of Tenure Track, University of Miyazaki, Miyazaki 889-1692, Japan.
Kimiko HonshoOrganization for Promotion of Tenure Track, University of Miyazaki, Miyazaki 889-1692, Japan.
Ah-Reum LeeOrganization for Promotion of Tenure Track, University of Miyazaki, Miyazaki 889-1692, Japan.
Hiroki NabekuraOrganization for Promotion of Tenure Track, University of Miyazaki, Miyazaki 889-1692, Japan.
Hiroshi OhtaDepartment of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
Tomoyuki TsukiyamaDepartment of Stem Cells and Human Disease Models, Research Center for Animal Life Science, Shiga University of Medical Science, Seta, Tsukinowa-cho, Otsu, Shiga 520-2192, Japan.
Yasuhide OhinataLaboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.
Asato KuroiwaDivision of Reproductive and Developmental Biology, Department of Biological Sciences, Faculty of Science, Hokkaido University, Sapporo, Japan.
Yoshitaka HishikawaDepartment of Histochemistry and Cell Biology, Department of Anatomy, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan.ORCID 0000-0002-3796-6234
Mitinori SaitouDepartment of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
Takamichi JogaharaDivision of Bio-Resources, Frontier Science Research Center, University of Miyazaki, Miyazaki 889-1692, Japan.
Chihiro KoshimotoDivision of Bio-Resources, Frontier Science Research Center, University of Miyazaki, Miyazaki 889-1692, Japan.
University of Miyazaki · JPKyoto University · JPHokkaido University · JPRIKEN Center for Integrative Medical Sciences · JPShiga University of Medical Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In mammals, the Y chromosome strictly influences the maintenance of male germ cells. Almost all mammalian species require genetic contributors to generate testes. An endangered species,

Indexed as

Chromosomes, MammalianEndangered SpeciesMurinaeX ChromosomeAnimalsFemaleGerm CellsInduced Pluripotent Stem CellsMaleSex Determination ProcessesTestischimeraEndangered speciesgerm cellsinduced pluripotent stem cellssex determinationTokudaia osimensis

Identifiers

PMID28508054
PMCPMC5429033
OpenAlexW2612208361

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.