ArticleScience advances2017
Mechanism and color modulation of fungal bioluminescence.
Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 106 citations in OpenAlex.
- Metabolically robust ratiometric autoluminescent reporters.Nature plants · 2026Article
- Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway.The FEBS journal · 2026Article
- Microbial bioindicators for multidimensional assessment of environmental alterations and ecosystem functioning.World journal of microbiology & biotechnology · 2026Review
- Non-invasive imaging of defence responses in plants.Nature communications · 2026Article
- Sustainable bioenergy manufacturing in plants.Plant communications · 2026Review
- Autonomous Bioluminescence Systems: From Molecular Mechanisms to Emerging Applications.JACS Au · 2025Review
- Spore-Derived Isolates from a Single Basidiocarp of BioluminescentMicroorganisms · 2025Article
- Diversity, Distribution, and Evolution of Bioluminescent Fungi.Journal of fungi (Basel, Switzerland) · 2024Review
- Glowing wonders: exploring the diversity and ecological significance of bioluminescent organisms in Brazil.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024Review
- Sculpting photoproducts with DNA origami.Chem · 2024Article
- A Comprehensive Exploration of Bioluminescence Systems, Mechanisms, and Advanced Assays for Versatile Applications.Biochemistry research international · 2024Review
- Article
- Triple Reporter Assay: A Non-Overlapping Luciferase Assay for the Measurement of Complex Macromolecular Regulation in Cancer Cells Using a New Mushroom Luciferase-Luciferin Pair.Sensors (Basel, Switzerland) · 2023Article
- Metabolic engineering and mechanical investigation of enhanced plant autoluminescence.Plant biotechnology journal · 2023Article
- The Luminous Fungi of Japan.Journal of fungi (Basel, Switzerland) · 2023Review
- Ultrasound triggered organic mechanoluminescence materials.Advanced drug delivery reviews · 2022Review
- Theoretical Study of the Thermolysis Reaction and Chemiexcitation of Coelenterazine Dioxetanes.The journal of physical chemistry. A · 2022Article
- Finding the Light Emission Stimulator of Neonothopanus nambi Basidiomycete and Studying Its Properties.Doklady. Biochemistry and biophysics · 2022Article
- An Autonomous Molecular Bioluminescent Reporter (AMBER) for Voltage Imaging in Freely Moving Animals.Advanced biology · 2021Article
- Bioluminescence and Photoreception in Unicellular Organisms: Light-Signalling in a Bio-Communication Perspective.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
26 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioluminescent fungi are spread throughout the globe, but details on their mechanism of light emission are still scarce. Usually, the process involves three key components: an oxidizable luciferin substrate, a luciferase enzyme, and a light emitter, typically oxidized luciferin, and called oxyluciferin. We report the structure of fungal oxyluciferin, investigate the mechanism of fungal bioluminescence, and describe the use of simple synthetic α-pyrones as luciferins to produce multicolor enzymatic chemiluminescence. A high-energy endoperoxide is proposed as an intermediate of the oxidation of the native luciferin to the oxyluciferin, which is a pyruvic acid adduct of caffeic acid. Luciferase promiscuity allows the use of simple α-pyrones as chemiluminescent substrates.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.