Evidence map›Paper›PMID 28507749›Full record

ArticleUnited European gastroenterology journal2017

Splenic volume differentiates complicated and non-complicated celiac disease.

Tom van Gils, Petula Nijeboer, Jan Hein Tm van Waesberghe, Veerle Mh Coupé, Kiki Janssen, Jessy A Zegers, Shaikh A Nurmohamed, Georg Kraal, Sabine Ci Jiskoot, Gerd Bouma and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in United European gastroenterology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Review
  5. Review article: Follow-up of coeliac disease.Alimentary pharmacology & therapeutics · 2022
    Review
  6. Article
  7. Refractory Celiac Disease.Current gastroenterology reports · 2020
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Tom van GilsCeliac Center Amsterdam, Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
Petula NijeboerCeliac Center Amsterdam, Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
Jan Hein Tm van WaesbergheDepartment of Radiology, VU University Medical Center, Amsterdam, The Netherlands.
Veerle Mh CoupéDepartment of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.
Kiki JanssenCeliac Center Amsterdam, Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
Jessy A ZegersCeliac Center Amsterdam, Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
Shaikh A NurmohamedDepartment of Nephrology, VU University Medical Center, Amsterdam, The Netherlands.
Georg KraalDepartment of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands.
Sabine Ci JiskootDepartment of Radiology, VU University Medical Center, Amsterdam, The Netherlands.
Gerd BoumaCeliac Center Amsterdam, Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
Chris Jj MulderCeliac Center Amsterdam, Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
Amsterdam UMC Location Vrije Universiteit Amsterdam · NLJan de Rijk Logistics (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies in small groups of patients indicated that splenic volume (SV) may be decreased in patients with celiac disease (CD), refractory CD (RCD) type II and enteropathy-associated T-cell lymphoma (EATL).

objectiveThe objective of this article is to evaluate SV in a large cohort of uncomplicated CD, RCD II and EATL patients and healthy controls.

methodsThe retrospective cohort consisted of 77 uncomplicated CD (of whom 39 in remission), 29 RCD II, 24 EATL and 12 patients with both RCD II and EATL. The control group included 149 healthy living kidney donors. SV was determined on computed tomography.

resultsThe median SV in the uncomplicated CD group was significantly larger than in controls (202 cm

conclusionThis study demonstrates large inter-individual variation in SV. SV is enlarged in uncomplicated CD. The small SV in RCD II may be of clinical relevance considering the immune-compromised status of these patients.

Indexed as

Celiac diseasecomputed tomographyenteropathy-associated T-cell lymphomarefractory celiac diseasespleensplenic volume

Identifiers

PMID28507749
PMCPMC5415212
OpenAlexW2514553325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.